Evidence mapPaperPMID 42132201Full record

ReviewCardiovascular therapeutics2026

Hotspots Evolution and Cutting-Edge Trends: A Bibliometric Analysis of Autophagy in Myocardial Infarction Studies From 2007 to 2025.

Xiao-Lin Li, Jin-Wen Wu, Zeng-Dai-Quan Ke, Yuan-Li Hu, Hang Jiang, Ming-Tai Chen, Han-Yu Hu, Zhong-Jing Hu, Yuan-Yuan Li, Gang Luo and 1 more

Abstract readReview
In one paragraph

Review in Cardiovascular therapeutics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xiao-Lin LiDepartment of Cardiology, The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, Sichuan, China, swmu.edu.cn.ORCID https://orcid.org/0009-0005-6816-7653
Jin-Wen WuDepartment of Cardiology, The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, Sichuan, China, swmu.edu.cn.ORCID https://orcid.org/0000-0002-7875-1598
Zeng-Dai-Quan KeSchool of Integrated Traditional Chinese and Western Medicine, Southwest Medical University, Luzhou, Sichuan, China, swmu.edu.cn.ORCID https://orcid.org/0009-0005-8638-0052
Yuan-Li HuSchool of Integrated Traditional Chinese and Western Medicine, Southwest Medical University, Luzhou, Sichuan, China, swmu.edu.cn.ORCID https://orcid.org/0009-0002-6378-0510
Hang JiangSchool of Integrated Traditional Chinese and Western Medicine, Southwest Medical University, Luzhou, Sichuan, China, swmu.edu.cn.ORCID https://orcid.org/0009-0006-3419-7472
Ming-Tai ChenFaculty of Chinese Medicine and State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau, China, must.edu.mo.ORCID https://orcid.org/0000-0003-4579-5559
Han-Yu HuSchool of Integrated Traditional Chinese and Western Medicine, Southwest Medical University, Luzhou, Sichuan, China, swmu.edu.cn.ORCID https://orcid.org/0009-0005-9167-4397
Zhong-Jing HuDepartment of Cardiology, The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, Sichuan, China, swmu.edu.cn.ORCID https://orcid.org/0009-0000-6594-3374
Yuan-Yuan LiGuangdong-Macao ln-Depth Cooperation Zone in Hengqin, Chinese Medicine Guangdong Laboratory (Hengqin Laboratory), Zhuhai, Guangdong, China.ORCID https://orcid.org/0009-0003-6958-2889
Gang LuoDepartment of Cardiology, The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, Sichuan, China, swmu.edu.cn.ORCID https://orcid.org/0000-0002-0487-2311
Meng-Nan LiuDepartment of Cardiology, The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, Sichuan, China, swmu.edu.cn.ORCID https://orcid.org/0000-0001-9991-642X

Funding

2024 Traditional Chinese Medicine Guangdong Provincial Laboratory Project HQCML-C-2024005Department of Science and Technology of Sichuan Province 2026NSFSC1823National Natural Science Foundation of China 82074378Shenzhen Medical Research Fund A2403028Shenzhen Science and Technology Innovation Program JCYJ20230807094603007Shenzhen Science and Technology Innovation Program JCYJ20240813152440051Southwest Medical University 2024ZKY073Southwest Medical University 2024ZKZ007Southwest Medical University 2024ZXYZX30Southwest Medical University 2024ZXYZX39Youth Innovation Project of Sichuan Medical Association Q20250014
6 · The paper itself

Abstract

backgroundMyocardial infarction (MI), a severe cardiovascular disorder, has a well-established association with autophagy and disease progression. However, bibliometric analyses of this relationship remain limited.

methodsAll literature related to autophagy in MI published between 2007 and 2025 was collected from the Web of Science Core Collection (WoSCC) and Scopus. The final database search was conducted on December 31, 2025. HistCite Pro, CiteSpace, VOSviewer, SCImago Graphica, and Origin were used for bibliometric analysis and visualization.

resultsThis search identified 649 publications on autophagy in MI. China was the most productive country, with Harbin Medical University as the leading institution. Researchers from Japan also made substantial contributions. Biochemical and Biophysical Research Communications published the highest number of articles. Sadoshima, Junichi was the most active researcher in this field. Current research hotspots include "oxidative stress" (the most recent focus) and "survival" (with the strongest citation bursts).

conclusionsThis bibliometric analysis synthesizes research trends in autophagy-related MI studies from 2007 to 2025. Future research should prioritize elucidating the mechanistic roles of autophagy in MI, particularly the interplay between mitophagy and the NLRP3 (NOD-like receptor family pyrin domain-containing Protein 3) pathway, to facilitate the development of more effective clinical interventions.

Indexed as

AutophagyBiomedical ResearchMyocardial InfarctionPeriodicals as TopicAnimalsBibliometricsHumansTime Factorsautophagybibliometric analysiscardioprotectionmyocardial infarction

Identifiers

PMID42132201
PMCPMC13173547

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.