ArticleBiologia futura2026
Therapeutic effects of bee venom on high fat diet induced obesity and behavioral changes.
Article in Biologia futura, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
This study aimed to explore the potential effects of bee venom (BV) and cold exposure (CE) on behavioral and physiological alterations induced by a high-fat diet (HFD) in rats. Three-week-old male Sprague-Dawley rats were assigned to seven groups: Control, CE, BV, HFD, HFD+CE, HFD+BV and HFD+CE+BV. Anxiety- and depression-like behaviors were evaluated using the open field, elevated plus maze and forced swim tests. HFD increased anxiety and depression like behaviors, whereas BV administration alleviated these alterations. HFD also elevated plasma triglycerides, total cholesterol, LDL, glucose, insulin and leptin levels while reducing HDL concentrations. BV treatment improved these metabolic parameters. Histological analysis revealed enlarged adipocyte diameters in both white (WAT) and brown (BAT) adipose tissues in HFD-fed rats, which were reduced following BV administration. Moreover, BV enhanced UCP-1 gene expression in BAT and WAT, particularly under CE conditions, suggesting increased thermogenic activity. These findings indicate that BV may exert beneficial effects on HFD-induced metabolic dysfunctions and behavioural alterations, possibly through modulation of adipose tissue function and thermogenesis. The combination of BV and CE may represent a potential therapeutic approach for managing obesity associated physiological and behavioral disorders.
Indexed as
Identifiers
42133199What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.