ArticleScientific reports2026
Urinary potassium/urinary creatinine ratio in outpatients with heart failure: factors associated and prognostic implications.
Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
The spot urinary potassium-to-creatinine (uK/uCr) ratio has been proposed as a surrogate for 24-h potassium excretion, but its clinical determinants and prognostic significance in heart failure (HF) remain unclear. We evaluated the clinical variables associated with the uK/uCr ratio and its relationship with long-term mortality in ambulatory HF patients. We ambispectively analyzed 1,145 patients from a single-center HF clinic. A multivariable linear regression model was used to identify factors independently associated with the uK/uCr ratio, and Cox models assessed its prognostic value. Mean age was 73.2 ± 11.3 years, 41.5% were women, and 52.0% had HF with preserved ejection fraction. Median NT-proBNP and uK/uCr were 1324 (447-2952) pg/mL and 48 (36-62) mmol/g creatinine, respectively. Higher uK/uCr was independently associated with estimated glomerular filtration rate (28.3% of R
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