Evidence map›Paper›PMID 42135539›Full record

ArticleNature metabolism2026

Human whole-blood NAD

Maria M Trętowicz, Angelique M L Scantlebery, Bauke V Schomakers, Kaan D Eroğlu, Michel van Weeghel, Vera Spek, Kasper T Vinten, Luc Legon, Evrim Coskun, Fernando Millan-Domingo and 22 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature metabolism, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

32 authors.

Maria M TrętowiczLaboratory Genetic Metabolic Diseases, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.ORCID http://orcid.org/0009-0007-1244-2147
Angelique M L ScantleberyLaboratory Genetic Metabolic Diseases, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Bauke V SchomakersLaboratory Genetic Metabolic Diseases, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Kaan D EroğluLaboratory Genetic Metabolic Diseases, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Michel van WeeghelLaboratory Genetic Metabolic Diseases, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.ORCID http://orcid.org/0000-0002-4916-2866
Vera SpekLaboratory Genetic Metabolic Diseases, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.ORCID http://orcid.org/0009-0005-1050-6667
Kasper T VintenLaboratory Genetic Metabolic Diseases, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.ORCID http://orcid.org/0000-0001-9661-4709
Luc LegonLaboratory Genetic Metabolic Diseases, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.ORCID http://orcid.org/0000-0001-7489-5781
Evrim CoskunLaboratory Genetic Metabolic Diseases, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.ORCID http://orcid.org/0000-0002-8133-1500
Fernando Millan-DomingoFreshage Research Group, Department of Physiology, Faculty of Medicine, University of Valencia, CIBERFES, Fundación Investigación Hospital Clínico Universitario/INCLIVA, Valencia, Spain.ORCID http://orcid.org/0000-0002-7541-0704
Gloria Olaso-GonzalezFreshage Research Group, Department of Physiology, Faculty of Medicine, University of Valencia, CIBERFES, Fundación Investigación Hospital Clínico Universitario/INCLIVA, Valencia, Spain.
Maria Carmen Gomez-CabreraFreshage Research Group, Department of Physiology, Faculty of Medicine, University of Valencia, CIBERFES, Fundación Investigación Hospital Clínico Universitario/INCLIVA, Valencia, Spain.ORCID http://orcid.org/0000-0003-4000-1684
Silvia Montoro-GarcíaPreclinical Research of Bioactive Compounds and Drugs (PREBIOF), Izpisúa Lab HiTech, Faculty of Health Sciences, Universidad Católica de Murcia (UCAM), Campus los Jerónimos, Murcia, Spain.
Clara Noguera-NavarroPreclinical Research of Bioactive Compounds and Drugs (PREBIOF), Izpisúa Lab HiTech, Faculty of Health Sciences, Universidad Católica de Murcia (UCAM), Campus los Jerónimos, Murcia, Spain.
André B P van KuilenburgAmsterdam Gastroenterology, Endocrinology, Metabolism, Amsterdam, The Netherlands.ORCID http://orcid.org/0000-0002-7989-4910
Sofia MocoChemistry and Pharmaceutical Sciences Department, Amsterdam Institute of Molecular and Life Sciences (AIMMS), Vrije Universiteit (VU) Amsterdam, Amsterdam, the Netherlands.ORCID http://orcid.org/0000-0001-8170-8876
Juliette C van HattumDepartment of Cardiology, Amsterdam UMC, University of Amsterdam. Amsterdam Movement Sciences Institute, Amsterdam Cardiovascular Sciences Institute, Amsterdam, The Netherlands.
Harald T JørstadDepartment of Cardiology, Amsterdam UMC, University of Amsterdam. Amsterdam Movement Sciences Institute, Amsterdam Cardiovascular Sciences Institute, Amsterdam, The Netherlands.ORCID http://orcid.org/0000-0003-3617-3256
Mohammed BenaliDepartment of Nutrition and Dietetics, Faculty of Health, Sport and Physical Activity, Amsterdam University of Applied Sciences, Amsterdam, the Netherlands.
Jantine van der HelderDepartment of Nutrition and Dietetics, Faculty of Health, Sport and Physical Activity, Amsterdam University of Applied Sciences, Amsterdam, the Netherlands.
Esmee J M BierstekerDepartment of Nutrition and Dietetics, Faculty of Health, Sport and Physical Activity, Amsterdam University of Applied Sciences, Amsterdam, the Netherlands.
Maheswary MuniandyResearch Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki, Helsinki, Finland.ORCID http://orcid.org/0000-0001-7624-7948
Kirsi H PietiläinenResearch Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki, Helsinki, Finland.ORCID http://orcid.org/0000-0002-8522-1288
Eija PirinenResearch Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki, Helsinki, Finland.ORCID http://orcid.org/0000-0003-1495-3972
P Eline SlagboomSection of Molecular Epidemiology, Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands.ORCID http://orcid.org/0000-0002-2875-4723
Marian BeekmanSection of Molecular Epidemiology, Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands.ORCID http://orcid.org/0000-0003-0585-6206
Joris DeelenSection of Molecular Epidemiology, Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands.ORCID http://orcid.org/0000-0003-4483-3701
Rubén Zapata-PérezGroup of Metabolism and Gene Regulation, UCAM HiTech Sport & Health Innovation Hub, Universidad Católica de Murcia, Guadalupe de Maciascoque, Murcia, Spain.ORCID http://orcid.org/0000-0003-4432-9652
Peter J M WeijsDepartment of Nutrition and Dietetics, Faculty of Health, Sport and Physical Activity, Amsterdam University of Applied Sciences, Amsterdam, the Netherlands.
Michael TielandDepartment of Nutrition and Dietetics, Faculty of Health, Sport and Physical Activity, Amsterdam University of Applied Sciences, Amsterdam, the Netherlands.
Georges E JanssensLaboratory Genetic Metabolic Diseases, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands. g.e.janssens@amsterdamumc.nl.ORCID http://orcid.org/0000-0003-2104-8145
Riekelt H HoutkooperLaboratory Genetic Metabolic Diseases, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands. r.h.houtkooper@amsterdamumc.nl.ORCID http://orcid.org/0000-0001-9961-0842

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nicotinamide adenine dinucleotide (NAD

Indexed as

AgingLife StyleNADAdultAgedBiomarkersChromatography, High Pressure LiquidFemaleHumansMaleMass SpectrometryMiddle AgedNiacinamideBiomarkersNADNiacinamide

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.