Evidence mapPaperPMID 42136123Full record

ReviewImmunity, inflammation and disease2026

Probiotics Cancer Interaction, Prevention, and Therapy.

Mostafa Saebi, Amir Hossein Barjasteh, Mahmoud Mahmoudi, Ramiar Kamal Kheder, Setayesh Ramazanpour, Negar Ebadpour, Afsane Fadaee, Seyed-Alireza Esmaeili

Abstract readReview
In one paragraph

Review in Immunity, inflammation and disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Probiotics Cancer Interaction, Prevention, and Therapy.Immunity, inflammation and disease · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mostafa SaebiImmunology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Amir Hossein BarjastehImmunology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.ORCID https://orcid.org/0000-0002-3239-2622
Mahmoud MahmoudiImmunology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Ramiar Kamal KhederMedical Laboratory Science Department, College of Science, University of Raparin, Rania, Sulaymaniyah, Iraq.
Setayesh RamazanpourImmunology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Negar EbadpourImmunology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Afsane FadaeeImmunology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Seyed-Alireza EsmaeiliStudent Research Committee, Mashhad University of Medical Sciences, Mashhad, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer is a significant global health concern and ranks as the second most common cause of death on a worldwide scale. A combination of hereditary and lifestyle variables, such as diet, smoking, alcohol consumption, physical exercise, and the gut microbiota, impacts cancer development. Dysbiosis, an imbalance in gut microorganisms, can promote cancer. Conversely, probiotics have the potential to enhance gut health and restore immunological equilibrium. Prior research has demonstrated that probiotics exert a beneficial influence on gastrointestinal health and immunological function. Probiotics perform these beneficial actions by changing the kinds of bacteria that live in the gut, altering metabolic function, breaking down chemicals that cause cancer, enhancing the efficacy of immune checkpoint inhibitors, reducing inflammation, and stopping the production of compounds that cause cancer. This current comprehensive review underscores the need for innovative strategies to enhance cancer prevention and treatment, focusing on integrating probiotics into therapeutic approaches to mitigate the adverse effects of conventional cancer therapies, improve patient outcomes, and prevent cancer.

Indexed as

Gastrointestinal MicrobiomeNeoplasmsProbioticsAnimalsDysbiosisHumanscancer preventioncancer therapychemotherapygut microbiotaprobiotics

Identifiers

PMID42136123
PMCPMC13176637

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.