Evidence map›Paper›PMID 42136131›Full record

ArticleMaternal & child nutrition2026

Maternal Health and Sociodemographic Characteristics Influence Infant Growth to 24 Months in the Tunza Mwana Cohort: A Prospective Cohort Study.

David Taylor Hendrixson, Ruchi Tiwari, Philip James, Zulfiqar A Bhutta, André Briend, Sheila Isanaka, Tanya Khara, Natasha Lelijveld, Mark J Manary, Andrew Mertens and 8 more

Abstract read
In one paragraph

Article in Maternal & child nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

David Taylor HendrixsonDepartment of Pediatrics, University of Washington, Seattle, Washington, USA.
Ruchi TiwariDepartment of Global Health, University of Washington, Seattle, Washington, USA.ORCID 0000-0002-5251-7250
Philip JamesEmergency Nutrition Network, Oxford, UK.
Zulfiqar A BhuttaCenter for Global Child Health, Hospital for Sick Children, Toronto, Canada.ORCID 0000-0003-0637-599X
André BriendCenter for Child Health Research, Tampere University, Tampere, Finland.
Sheila IsanakaHarvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Tanya KharaEmergency Nutrition Network, Oxford, UK.
Natasha LelijveldEmergency Nutrition Network, Oxford, UK.
Mark J ManaryDepartment of Pediatrics, Washington University in St. Louis, St. Louis, Missouri, USA.
Andrew MertensSchool of Public Health, University of California Berkeley, Berkeley, California, USA.ORCID 0000-0002-1050-6721
Sophie E MooreKings College London, London, UK.
Kieran S O'BrienFrancis I. Proctor Foundation, University of California, San Francisco, California, USA.
Jonathan WellsGreat Ormond Street Institute of Child Health (ICH), University College London (UCL), London, UK.
Priscah LihandaKenya Medical Research Institute, Nairobi, Kenya.
Eric OcholaKenya Medical Research Institute, Nairobi, Kenya.
Grace AldrovandiDepartment of Pediatrics, University of California Los Angeles, Los Angeles, California, USA.
Benson O SingaKenya Medical Research Institute, Nairobi, Kenya.
Christine J McGrathDepartment of Global Health, University of Washington, Seattle, Washington, USA.

Funding

Effects of Human Milk Oligosaccharides and Gut Microbiome on Growth and Morbidity in HIV-Exposed Uninfected InfantsR01HD096999 · NICHD · UNIVERSITY OF WASHINGTON · PI ALDROVANDI, GRACE M, MCGRATH, CHRISTINE JENNIFER · 2019 to 2023
$3.6M
The effect of the maternal plasma and breastmilk metabolome on the infant gut microbiome and growthK23HD113374 · NICHD · UNIVERSITY OF WASHINGTON · PI David Taylor Hendrixson · 2023 to 2026
$644k
Association between adverse maternal factors and neurodevelopmental outcomes among children in KenyaF32HD116460 · NICHD · UNIVERSITY OF WASHINGTON · PI TIWARI, RUCHI · 2024 to 2025
$154k
Irish Aid HQPCR/2025/ENNNICHD NIH HHS F32 HD116460NICHD NIH HHS K23 HD113374NICHD NIH HHS R01 HD096999
6 · The paper itself

Abstract

Upstream pathways influencing child growth are complex. Weight-for-age z-score (WAZ) reflects both ponderal and linear growth and can identify children at high mortality risk. Using data from a prospective cohort of 326 mother-child pairs in Kenya, we evaluated whether associations between maternal exposures and child growth outcomes in early and later childhood. Growth trajectories were examined using locally weighted scatterplot smoothing and piecewise linear mixed-effect models with a knot at age 3 months. Poisson regression models examined associations between maternal characteristics and child underweight (WAZ < -2) and stunting (LAZ < -2) before and after 3 months. Mean WAZ increased to a peak at 3 months before declining steadily through 24 months. Lower maternal education (adjusted β [aβ] -0.18; 95% CI: -0.24, -0.13), household crowding (aβ -0.2; 95% CI: -0.28, -0.11), lower wealth quintile (aβ -0.04; 95% CI: -0.06, -0.02) and multiparity (aβ -0.16; 95% CI: -0.23, -0.1) were associated with lower monthly rate of change in WAZ prior to age 3 months. Younger maternal age was associated with an increased monthly rate of change in WAZ (aβ = 0.13; 95% CI: 0.08, 0.18) before 3 months and decreased monthly WAZ (aβ -0.02; 95% CI: -0.03, -0.01) after 3 months. Preterm birth was associated with increased risk of underweight in both periods (aRR 2.77; 95% CI: 1.39-5.50). Maternal mental health, intimate partner violence and adverse childhood experiences were not significantly associated with child growth. Maternal nutritional, socio-economic and household-level factors shape early growth, emphasising the need for cross-sectoral programs to support growth.

Indexed as

Child DevelopmentMaternal HealthSociodemographic FactorsAdultEducational StatusFamily CharacteristicsFemaleHumansIncomeInfantInfant, NewbornKenyaMaleMaternal AgeMaternal ExposureMaternal Nutritional Physiological Phenomenainfant growthKenyamaternal healthstuntingunderweightwasting

Identifiers

PMID42136131
PMCPMC13176631

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.