ArticleInternational journal of molecular medicine2026
CircRAD18 promotes glioblastoma proliferation, migration and invasion via the miR‑1231/LUC7L2 axis.
Article in International journal of molecular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Sphingosine-1-phosphate induces angiogenesis via the activating STAT3 signaling pathway to drive colorectal cancer progression.Journal of gastrointestinal oncology · 2026Article
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Authors and funding
13 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Glioblastoma (GBM) is an exceptionally aggressive and malignant central nervous system tumor with a poor prognosis. Studies suggest that circular RNAs (circRNAs) play a vital role in GBM progression. Exosomes, key mediators of intercellular communication, carry circRNAs that may regulate this process. The present study aimed to investigate how circRAD18 modulates GBM cell proliferation, migration and invasion through the miR‑1231/LUC7L2 axis and to evaluate the potential of exosomal circRAD18 as a diagnostic biomarker for GBM. Bioinformatics analyses identified differentially expressed circRAD18, miR‑1231 and LUC7L2 in GBM and predicted their interactions. Expression levels were assessed using western blot analysis, immunohistochemistry and reverse transcription‑quantitative polymerase chain reaction. Regulatory mechanisms were examined via dual‑luciferase reporter assays, RNA pull‑down assays, CCK‑8 assays, wound healing assays, Transwell assays, fluorescence
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