Evidence map›Paper›PMID 42138558›Full record

ArticleLasers in surgery and medicine2026

Clinical Outcomes of Fractional Carbon Dioxide Laser Treatment in Women With Vulvar Lichen Simplex Chronicus: A Retrospective Study With 12-Month Follow-Up.

Nengxiu Wu, Siai Chen, Chaoqin Lin, Qi Wang

Abstract read
In one paragraph

Article in Lasers in surgery and medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nengxiu WuFujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, Fujian Province, China.ORCID https://orcid.org/0009-0000-6724-2125
Siai ChenFujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, Fujian Province, China.
Chaoqin LinFujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, Fujian Province, China.ORCID https://orcid.org/0000-0003-4631-0218
Qi WangFujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, Fujian Province, China.ORCID https://orcid.org/0000-0003-3175-2881

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the efficacy and safety of fractional carbon dioxide (CO

methodsThis retrospective study included 88 women with VLSC who underwent three sessions of fractional CO

resultsAt 1, 6, and 12 months post-treatment, significant reductions were observed in VAS scores for vulvar pruritus and dyspareunia, as well as in Cattaneo clinical symptom and sign scores (all p < 0.05). The overall response rates were 89.8% (79/88; 95% confidence interval [CI], 81.7%-94.5%), 93.2% (82/88; 95% CI, 85.9%-96.8%), and 88.6% (78/88; 95% CI, 80.3%-93.7%), respectively. According to the PGI-C questionnaire, the proportions of patients reporting improvement or marked improvement were 72.7%, 78.4%, and 70.5% at the corresponding follow-up time points. No significant differences in treatment outcomes were observed according to disease duration or menopausal status.

conclusionFractional CO

Indexed as

Lasers, GasNeurodermatitisAdultAgedFemaleFollow-Up StudiesHumansMiddle AgedRetrospective StudiesTreatment Outcomedyspareuniafractional carbon dioxide laserpatient‐reported outcomesvulvar lichen simplex chronicusvulvar pruritus

Identifiers

PMID42138558
PMCPMC13465984

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.