Evidence map›Paper›PMID 42138736›Full record

ArticleArchives of orthopaedic and trauma surgery2026

Sex-related differences in final knee balance during robotic-assisted unicompartmental knee arthroplasty.

Davide Stimolo, Filippo Leggieri, Gregorio Secci, Marta Massenzi, Roberto Civinini, Matteo Innocenti

Abstract read
In one paragraph

Article in Archives of orthopaedic and trauma surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Davide StimoloDepartment of Orthopaedics, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy. davide.stimolo@unifi.it.
Filippo LeggieriSchool of Human Health Sciences, University of Florence, Florence, Italy.
Gregorio SecciSchool of Human Health Sciences, University of Florence, Florence, Italy.
Marta MassenziSchool of Human Health Sciences, University of Florence, Florence, Italy.
Roberto CivininiSchool of Human Health Sciences, University of Florence, Florence, Italy.
Matteo InnocentiSchool of Human Health Sciences, University of Florence, Florence, Italy. matteo.innocenti@unifi.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIn robotic medial unicompartmental knee arthroplasty (mUKA), a preoperative alignment strategy can be defined and subsequently adjusted through stress testing to achieve optimal soft-tissue balance. However, the application of uniform planning principles does not necessarily yield equivalent balance in all patients. The aim of this study was to examine differences in intraoperative balance according to patient sex and the degree of preoperative varus deformity. MATERIALS AND

methodsA single-center retrospective cohort study including 254 MAKO

resultsMean preoperative alignment was 174.2 ± 2.8°, with no sex-related difference in baseline varus (p = 0.058). Flexion gaps were significantly tighter in female patients (p = 0.0045). A tight F90 gap was observed in 17.2% more female than male patients (p = 0.023), with an absolute mean difference of 0.35 mm (95% CI - 0.62 to - 0.11 mm). Multivariate linear regression and multinomial logistic regression confirmed tighter F90 gaps in female patients (β = -0.38; 95% CI - 0.63 to - 0.14; p = 0.002; OR = 2.25; 95% CI 1.30-3.88; p = 0.0036, respectively). Patient sex did not influence the extension gap (p = 0.686). Increasing preoperative varus showed a potential association with tighter extension spaces (ANOVA p = 0.0064), but not with flexion balance. The operating surgeon significantly influenced both extension and flexion gaps.

conclusionFemale patients tended to present a tighter flexion gap at 90° in robotic-assisted medial unicompartmental knee arthroplasty. Although the absolute difference was small, it was measurable, suggesting that studies focused on clinical outcomes will be needed to justify adjustments in the execution of mUKA in female patients. Surgeon-related decisions continued to exert a measurable influence on results.

Indexed as

Arthroplasty, Replacement, KneeKnee JointOsteoarthritis, KneeRobotic Surgical ProceduresAgedFemaleHumansMaleMiddle AgedRange of Motion, ArticularRetrospective StudiesSex Factorsgap balancingMedial unicompartmental knee arthroplastyrobot-assisted knee arthroplastysex differencessoft-tissue balance

Identifiers

PMID42138736
PMCPMC13179257

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.