Evidence map›Paper›PMID 42138755›Full record

SynthesisArchives of women's mental health2026

Multidimensional psychological and neurophysiological effects of moderate- and low-intensity exercise on pregnant women: an integrative systematic review and Bayesian framework network meta-analysis.

Lei He, Shiping Wang, Yuang Cao, Bolun Wang, Hongyang Liu, Jia Zhang, Feng Xu, Junfeng Jiao

Abstract readSystematic ReviewNetwork Meta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Archives of women's mental health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lei He *Department of Physical, Woosuk University, Jeonju, Republic of Korea.ORCID 0009-0009-4011-5543
Shiping Wang *Department of Physical, Woosuk University, Jeonju, Republic of Korea.
Yuang CaoDepartment of Physical, Woosuk University, Jeonju, Republic of Korea.
Bolun WangDepartment of Physical, Woosuk University, Jeonju, Republic of Korea.
Hongyang LiuDepartment of Physical, Woosuk University, Jeonju, Republic of Korea.
Jia ZhangChongqing University, Chongqing, China.
Feng XuPhysical Education Department, Shanghai Maritime University, Shanghai, China. fengxu@shmtu.edu.cn.
Junfeng JiaoPhysical Education Department, Anhui Sanlian University, Hefei, China. jiaojunfeng944@foxmail.com.

Funding

Fundamental Research Funds for the Central Universities 2024CDJSKXYTY03
6 · The paper itself

Abstract

backgroundPregnancy-related mental health disorders are an increasingly important global public health concern. Exercise interventions have gained attention as safe, non-pharmacological strategies for improving maternal psychological and neurophysiological well-being. However, comparative evidence regarding different exercise modalities and intensities remains limited.

objectiveThis study aimed to systematically evaluate and rank the effects of different prenatal exercise modalities and compare moderate- versus low-intensity exercise protocols on maternal mental health and neurophysiological outcomes during pregnancy.

methodsA Bayesian network meta-analysis was conducted following PRISMA-NMA guidelines. PubMed, Embase, Cochrane Central, and PsycINFO were systematically searched. Thirty-six randomized controlled trials involving 4,577 pregnant participants were included. Methodological quality was assessed using the Cochrane RoB 2.0 tool. Treatment effects were ranked using the surface under the cumulative ranking curve method.

resultsModerate-intensity aerobic training showed the strongest effect on reducing prenatal depression, with a SUCRA value of 0.89. Yoga-based interventions were particularly effective for anxiety reduction, with a SUCRA value of 0.76, and ranked second in the overall outcome evaluation, with a SUCRA value of 0.82. Neurophysiological findings indicated that yoga showed the greatest benefit for cortisol regulation, whereas aquatic exercise demonstrated distinctive anti-inflammatory effects. Subgroup analyses suggested that moderate-intensity exercise tended to produce greater reductions in depression, while low-intensity exercise showed comparable or superior effects on anxiety and cortisol modulation. Meta-regression further indicated that interventions conducted three times per week and lasting more than 12 weeks were associated with larger effect sizes. The certainty of evidence ranged from moderate to high across primary comparisons.

conclusionThis network meta-analysis provides a preliminary evidence hierarchy for prenatal exercise interventions. Moderate-intensity aerobic exercise may be most beneficial for reducing prenatal depression, while yoga appears particularly suitable for anxiety and cortisol regulation. These findings offer clinicians a reference framework for individualized prenatal exercise recommendations and support the integration of exercise into maternal mental healthcare.

Indexed as

ExerciseExercise TherapyPregnancy ComplicationsPregnant PeopleAnxietyBayes TheoremDepressionFemaleHumansMental HealthPregnancyRandomized Controlled Trials as TopicYogaEvidence-based medicineExercise interventionMental healthNetwork meta-analysisPregnancyPrenatal depression

Identifiers

PMID42138755

What Socratic holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.