Evidence map›Paper›PMID 42139343›Full record

ArticleScience advances2026

A BBB-permeable β

Wei Cheng, Zhuoying Chen, Yani Liu, Xiangjie Luo, Zheng Li, Huiquan Yang, Yifan Zhong, Xinyi Cai, Zhigang Sun, Ling Zhou and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Wei ChengState Key Laboratory of Microbial Technology, Department of Radiology, Nanjing Drum Tower Hospital, Jiangsu Collaborative Innovation Center of Biomedical Functional Materials, School of Chemistry and Materials Science, Nanjing Normal University, Nanjing 210023, China.ORCID 0000-0003-1037-8122
Zhuoying ChenState Key Laboratory of Microbial Technology, Department of Radiology, Nanjing Drum Tower Hospital, Jiangsu Collaborative Innovation Center of Biomedical Functional Materials, School of Chemistry and Materials Science, Nanjing Normal University, Nanjing 210023, China.ORCID 0009-0007-2707-1596
Yani LiuState Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Xianlin Road 163, Nanjing 210023, China.
Xiangjie LuoState Key Laboratory of Microbial Technology, Department of Radiology, Nanjing Drum Tower Hospital, Jiangsu Collaborative Innovation Center of Biomedical Functional Materials, School of Chemistry and Materials Science, Nanjing Normal University, Nanjing 210023, China.ORCID 0009-0006-0266-2536
Zheng LiState Key Laboratory of Microbial Technology, Department of Radiology, Nanjing Drum Tower Hospital, Jiangsu Collaborative Innovation Center of Biomedical Functional Materials, School of Chemistry and Materials Science, Nanjing Normal University, Nanjing 210023, China.
Huiquan YangDepartment of Radiology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing 210008, China.
Yifan ZhongState Key Laboratory of Microbial Technology, Department of Radiology, Nanjing Drum Tower Hospital, Jiangsu Collaborative Innovation Center of Biomedical Functional Materials, School of Chemistry and Materials Science, Nanjing Normal University, Nanjing 210023, China.
Xinyi CaiState Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Xianlin Road 163, Nanjing 210023, China.
Zhigang SunCentral Laboratory, Linyi Central Hospital, No. 17 Jiankang Road, Linyi 276400, China.ORCID 0000-0003-1640-757X
Ling ZhouState Key Laboratory of Microbial Technology, Department of Radiology, Nanjing Drum Tower Hospital, Jiangsu Collaborative Innovation Center of Biomedical Functional Materials, School of Chemistry and Materials Science, Nanjing Normal University, Nanjing 210023, China.
Bing ZhangDepartment of Radiology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing 210008, China.
Hai-Liang ZhuState Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Xianlin Road 163, Nanjing 210023, China.
Minyong LiDepartment of Medicinal Chemistry, Key Laboratory of Chemical Biology (MOE), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, China.
Yong QianState Key Laboratory of Microbial Technology, Department of Radiology, Nanjing Drum Tower Hospital, Jiangsu Collaborative Innovation Center of Biomedical Functional Materials, School of Chemistry and Materials Science, Nanjing Normal University, Nanjing 210023, China.ORCID 0000-0003-3788-3575

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

β

Indexed as

Blood-Brain BarrierBrain NeoplasmsGlioblastomaReceptors, Adrenergic, beta-3AnimalsApoptosisCell Line, TumorGlutathioneHumansMiceOxidation-ReductionOxidative StressSignal TransductionGlutathioneReceptors, Adrenergic, beta-3

Identifiers

PMID42139343
PMCPMC13178574

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.