In one paragraphArticle in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from itWhat it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
14 authors.
Irena SelicharováInstitute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Flemingovo n. 2, 16000 Praha 6, Czech Republic.ORCID 0000-0002-0180-6781 Anna KertisováInstitute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Flemingovo n. 2, 16000 Praha 6, Czech Republic.ORCID 0009-0001-8278-9652 Marta LubosInstitute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Flemingovo n. 2, 16000 Praha 6, Czech Republic.ORCID 0000-0002-2919-0085 Katarína MitrováInstitute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Flemingovo n. 2, 16000 Praha 6, Czech Republic.
Terezie TicháčkováInstitute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Flemingovo n. 2, 16000 Praha 6, Czech Republic.ORCID 0000-0003-2706-1295 Lenka ŽákováInstitute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Flemingovo n. 2, 16000 Praha 6, Czech Republic.ORCID 0000-0001-6439-2574 Martina ChrudinováInstitute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Flemingovo n. 2, 16000 Praha 6, Czech Republic.
Jana BřezinováInstitute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Flemingovo n. 2, 16000 Praha 6, Czech Republic.ORCID 0000-0002-2076-9891 Karel HarantInstitute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Flemingovo n. 2, 16000 Praha 6, Czech Republic.
Jan VoldřichInstitute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Flemingovo n. 2, 16000 Praha 6, Czech Republic.ORCID 0009-0006-9001-807X Miroslav HájekInstitute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Flemingovo n. 2, 16000 Praha 6, Czech Republic.ORCID 0000-0002-8906-243X Derek M HuffmanDepartment of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Jiří JiráčekInstitute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Flemingovo n. 2, 16000 Praha 6, Czech Republic.ORCID 0000-0003-3848-2773 Funding
Einstein's Nathan Shock Center of Excellence in Basic Biology of AgingP30AG038072 · NIA · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI CUERVO, ANA MARIA · 2010 to 2024
$10.8MNIA NIH HHS P30 AG038072
6 · The paper itselfAbstract
Insulin and insulin-like growth factors (IGF-1 and IGF-2) regulate metabolism, growth, and development via related receptors. In contexts such as brain function or fetal development, coordinated signaling by all three hormones is essential. We report the engineering of [GluB10, D-HisB24, GlyB31, TyrB32]-insulin (
Indexed as
InsulinProtein EngineeringReceptor, IGF Type 1Receptor, InsulinSignal TransductionAnimalsHumansMiceNeuronsProtein BindingRatsInsulinReceptor, IGF Type 1Receptor, Insulin
Identifiers
PMID42139356
PMCPMC13178572
What Socratic holds
Textmetadata
LicenceCC BY
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