Evidence map›Paper›PMID 42143150›Full record

ArticleNPJ digital medicine2026

Multi-task deep learning assists detection and diagnosis of gliomas and brain metastases.

Xiao Liu, Kun Lv, Peng Du, Kun Zhou, Qianru Zhao, Sen Jiao, Hongyi Chen, Danni Zhang, Hui Fang, Qiuyue Han and 9 more

Abstract read
In one paragraph

Article in NPJ digital medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Xiao Liu *Department of Radiology, Huashan Hospital, Qidong-Fudan Innovative Institute of Medical Sciences, Fudan University, Jingan District, China.
Kun Lv *Department of Radiology, Huashan Hospital, Qidong-Fudan Innovative Institute of Medical Sciences, Fudan University, Jingan District, China.
Peng DuDepartment of Radiology, the Second Affiliated Hospital of Xuzhou Medical University, Xuzhou City, China.
Kun ZhouCollege of biomedical engineering, Fudan University, Yangpu District, China.
Qianru ZhaoCollege of biomedical engineering, Fudan University, Yangpu District, China.
Sen JiaoCollege of biomedical engineering, Fudan University, Yangpu District, China.
Hongyi ChenZhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, China.
Danni ZhangDepartment of Radiology, Huashan Hospital, Qidong-Fudan Innovative Institute of Medical Sciences, Fudan University, Jingan District, China.
Hui FangDepartment of Radiology, Huashan Hospital, Qidong-Fudan Innovative Institute of Medical Sciences, Fudan University, Jingan District, China.
Qiuyue HanDepartment of Radiology, Huashan Hospital, Qidong-Fudan Innovative Institute of Medical Sciences, Fudan University, Jingan District, China.
Yanwei ZengDepartment of Radiology, Huashan Hospital, Qidong-Fudan Innovative Institute of Medical Sciences, Fudan University, Jingan District, China.
Xin CaoDepartment of Radiology, Huashan Hospital, Qidong-Fudan Innovative Institute of Medical Sciences, Fudan University, Jingan District, China.
Haiqing LiDepartment of Radiology, Huashan Hospital, Qidong-Fudan Innovative Institute of Medical Sciences, Fudan University, Jingan District, China.
Jian DaiCollege of biomedical engineering, Fudan University, Yangpu District, China.
Zhiji ZhengCollege of biomedical engineering, Fudan University, Yangpu District, China.
Hao WuDepartment of Dermatology, Huashan Hospital, Fudan University, Jingan District, China. seaseewh@163.com.
Xin WangDepartment of Neurosurgery, Huashan Hospital, Fudan University, Jingan District, China. wangxinck@fudan.edu.cn.
Yuxin LiDepartment of Radiology, Huashan Hospital, Qidong-Fudan Innovative Institute of Medical Sciences, Fudan University, Jingan District, China. liyuxin@fudan.edu.cn.
Daoying GengDepartment of Radiology, Huashan Hospital, Qidong-Fudan Innovative Institute of Medical Sciences, Fudan University, Jingan District, China. gengdy@163.com.

Funding

National Clinical Research Center for Aging and Medicine (Huashan Hospital) 2024KF2003National Nature Science Foundation of China 82372048Postdoctoral Fellowship Program of China Postdoctoral Science Foundation GZB20250515Qidong-Fudan Innovative Institute of Medical Sciences KTB002Science and Technology Commission of Shanghai Municipality 22TS1400900, 23S31904100, 22ZR1409500, 24SF1904200, 24SF1904201
6 · The paper itself

Abstract

Gliomas and brain metastases (BMs) on MRI pose significant diagnostic challenges for radiologists. This study aims to develop a multi-task model and a computer-aided diagnosis (CAD) system for the detection and diagnosis of gliomas and BMs. This study enrolled 3909 participants from seven centers, and developed a brain tumor segmentation and classification network (BTSC-Net) and BTSC-CAD with visualization of tumor masks. For detection, BTSC-Net achieved a Dice coefficient of 0.888 and 0.872 on the internal and external test sets, respectively. For diagnosis, BTSC-Net achieved AUCs of 0.941 and 0.933 on the internal and external test sets, respectively. With BTSC-CAD assistance, junior radiologists achieved mean AUC improvements of 4.8% (P < 0.05) for detection and 17.3% (P < 0.001) for diagnosis, along with an average reduction of 64.75 s in reading time. BTSC-CAD significantly improved radiologists' diagnostic accuracy and efficiency.

Identifiers

PMID42143150
PMCPMC13439454

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.