Evidence map›Paper›PMID 42144566›Full record

ArticlePest management science2026

BarH2 regulates odorant binding protein 6 expression to mediate 2,3-butanediol recognition in female Callosobruchus chinensis.

Yanan Yao, Chaoran Zhang, Yunfan Zhang, Xiaoyu Ma, Haixia Zheng, Penghua Bai, Xianhong Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pest management science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Yanan YaoCollege of Plant Protection, Shanxi Agricultural University, Taigu, China.ORCID https://orcid.org/0009-0001-5424-5308
Chaoran ZhangCollege of Plant Protection, Shanxi Agricultural University, Taigu, China.
Yunfan ZhangCollege of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
Xiaoyu MaCollege of Plant Protection, Shanxi Agricultural University, Taigu, China.
Haixia ZhengCollege of Plant Protection, Shanxi Agricultural University, Taigu, China.
Penghua BaiInstitute of Plant Protection, Tianjin Academy of Agricultural Sciences, Tianjin, China.ORCID https://orcid.org/0009-0008-3684-7453
Xianhong ZhangCollege of Plant Protection, Shanxi Agricultural University, Taigu, China.

Funding

Sub-Project of National Key Research and Development Program of China (2021YFD1600603-01)
6 · The paper itself

Abstract

backgroundThe insect olfactory system plays an important role in guiding chemical-driven behaviors, such as host selection, oviposition, and mating. Odorant-binding proteins (OBPs) serve as a bridge for transmitting chemical signals in insects; however, the transcriptional regulation of their expression patterns remains unknown.

resultsIn this study, we demonstrated that CchiBarH2 regulates the expression of CchiOBP6, mediating the olfactory recognition of female Callosobruchus chinensis for 2,3-butanediol. CchiBarH2 directly bound to the promoter region of CchiOBP6 and enhanced the transcriptional activity of CchiOBP6 in vitro using a dual-luciferase reporter system and electrophoretic mobility shift assay (EMSA). RNAi-mediated silencing of CchiBarH2 significantly decreased the expression level of CchiOBP6, weakened the electrophysiological responses, and the attraction of C. chinensis females to 2,3-butanediol disappeared simultaneously.

conclusionThese results revealed that CchiBarH2 regulated the expression of CchiOBP6, thereby mediating the EAG and behavioral responses of female C. chinensis to 2,3-butanediol. These findings also provide potential molecular targets for disrupting olfactory-driven behaviors in agricultural pest management. © 2026 Society of Chemical Industry.

Indexed as

Butylene GlycolsColeopteraGene Expression RegulationInsect ProteinsReceptors, OdorantAnimalsFemale2,3-butylene glycolButylene GlycolsInsect Proteinsodorant-binding proteinReceptors, OdorantCallosobruchus chinensisCchiBarH2odorant‐binding proteinolfactory recognitiontranscriptional regulation

Identifiers

PMID42144566
PMCPMC13453204

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.