ArticleCardiovascular diabetology2026
Joint association of atherogenic index of plasma (AIP) and body roundness index (BRI) with cardiometabolic multimorbidity in adults in Guangzhou, China.
Article in Cardiovascular diabetology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
Abstract
backgroundCardiometabolic multimorbidity (CMM) is one of the most prevalent patterns of multimorbidity worldwide and presents a growing challenge to public health. Metabolic dysregulation and visceral adipose play central roles in the development of CMM. The atherogenic index of plasma (AIP) has been proposed as a comprehensive indicator of lipid metabolic abnormalities, whereas the body roundness index (BRI) is a novel anthropometric measure reflecting central obesity and visceral adipose tissue (VAT). However, evidence regarding the associations of AIP and BRI with CMM remains limited, particularly in southern Chinese populations and young adults. This study examined the separate and joint associations of AIP and BRI with CMM, aiming to provide preliminary scientific evidence to identify individuals more likely to have prevalent CMM.
methodsThis cross-sectional study included 2505 adults from the 2024 Guangzhou Residents' Nutrition Survey. Multivariable logistic regression models and segmented logistic regression analyses were employed to examine the association patterns of AIP and BRI with CMM, as well as to assess potential threshold effects. For joint analysis, participants were categorized into four groups by AIP and BRI levels to evaluate the joint association and interaction between these indices and CMM.
resultsAmong the 2505 participants, 213 (8.50%) were diagnosed with CMM. Compared with the lowest tertile, the highest tertile of AIP (OR = 4.025, 95% CI 2.591-6.455) and BRI (OR = 10.461, 95% CI 5.523-22.496) were associated with a higher likelihood of CMM. AIP was linearly associated with CMM. In contrast, BRI demonstrated a nonlinear association with CMM, with an inflection point at 4.52, below which the odds of CMM increased more rapidly. Joint analyses revealed that participants in the "high AIP+high BRI" group had the strongest association with CMM (OR = 5.081, 95% CI 3.354-7.828). Subgroup analysis revealed that the association between the "high AIP+high BRI" group and CMM was stronger in participants < 60 years.
conclusionIndividuals with elevated levels of AIP and BRI are more likely to have CMM. AIP is linearly associated with CMM, whereas a threshold effect is observed for BRI. The joint assessment of AIP and BRI demonstrates a stronger association with CMM compared to either indicator alone. These findings suggest that the joint assessment of AIP and BRI may be a useful tool for identifying individuals at a higher likelihood of prevalent CMM, particularly in young and middle-aged adults.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.