Evidence map›Paper›PMID 42145645›Full record

ArticlemedRxiv : the preprint server for health sciences2026

Long-Read Haplotype Phasing Resolves Allelic Configuration as a Missing Layer of Precision Oncology.

Josh N Vo, Yi-Mi Wu, Rui Wang, Tiffany Pham, Xuhong Cao, Sophie Yeung, Mingyu Park, Yelena Kleyman-Smith, Guo Ci Teo, Alyssa Wu and 6 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors.

Josh N VoMichigan Center for Translational Pathology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Yi-Mi WuMichigan Center for Translational Pathology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Rui WangMichigan Center for Translational Pathology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Tiffany PhamMichigan Center for Translational Pathology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Xuhong CaoMichigan Center for Translational Pathology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Sophie YeungMichigan Center for Translational Pathology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Mingyu ParkMichigan Center for Translational Pathology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Yelena Kleyman-SmithMichigan Center for Translational Pathology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Guo Ci TeoMichigan Center for Translational Pathology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Alyssa WuMichigan Center for Translational Pathology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Anne LiMichigan Center for Translational Pathology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Jamie EstillMichigan Center for Translational Pathology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Lakshmi P KunjuDepartment of Pathology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Chen YangDepartment of Pathology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Dan R RobinsonMichigan Center for Translational Pathology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Arul M ChinnaiyanMichigan Center for Translational Pathology, University of Michigan Medical School, Ann Arbor, Michigan, USA.ORCID 0000-0001-9282-3415

Funding

Tissue/InformaticsP50CA186786 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Ganesh S Palapattu · 2014 to 2026
$27.6M
Exploring Precision Oncology: From Gene Fusions to lncRNAsR35CA231996 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CHINNAIYAN, ARUL M · 2018 to 2024
$6.4M
Michigan-VUMC Biomarker Characterization CenterU2CCA271854 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Jeffrey John Tosoian · 2022 to 2026
$5.4M
Integrative Multiomics and Clinical Laboratory Translation for Advanced, Rare, and Pediatric CancersR50CA293826 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Dan Russel Robinson · 2024 to 2026
$479k
NCI NIH HHS P50 CA186786NCI NIH HHS R35 CA231996NCI NIH HHS R50 CA293826NCI NIH HHS U2C CA271854
6 · The paper itself

Abstract

Conventional short-read sequencing cannot determine whether co-occurring variants within a cancer gene reside on the same allele (

Identifiers

PMID42145645
PMCPMC13174754

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.