ArticleFrontiers in nutrition2026
Galactose alters early-life development and exerts sex-specific nutritional programming effects on lifespan in
Article in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Nutritional programming by early-life nutrition exerts long-lasting effects on later-life health. In mammals, galactose, as a component of the milk sugar lactose, is consumed during lactation. Mouse studies suggest that prolonged postweaning galactose consumption improves later-life metabolic health, but it is unclear whether these benefits translate into increased lifespan. The fruit fly Methods: Results: In early-life, galactose consumption significantly prolonged larval development time, increased the pupal volume, reduced the pupal mitochondrial mass, and increased the energy expenditure of pupae in a body-weight-dependent manner. In adults fed a glucose diet, early-life galactose consumption significantly increased body weight, decreased whole-body TAG content, and reduced survival rate only in female flies, leaving males unaffected. These programming effects were absent when the adult flies were fed a high-glucose obesogenic diet. Conclusion: We newly show that dietary galactose has significant effects on early-life development of
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.