Evidence map›Paper›PMID 42146353›Full record

ArticlebioRxiv : the preprint server for biology2026

LongAllele: a joint inference framework for allele-specific analysis on long-read bulk and single-cell RNA sequencing.

Zhuoran Xu, Kai Wang

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Zhuoran XuGraduate Group in Genomics and Computational Biology, University of Pennsylvania, Philadelphia, PA, 19104, USA.ORCID 0000-0001-6733-541X
Kai WangRaymond G. Perelman Center for Cellular and Molecular Therapeutics, Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.ORCID 0000-0002-5585-982X

Funding

The Intellectual and Developmental Disabilities Research Center (IDDRC) at CHOP/PennP50HD105354 · NICHD · CHILDREN'S HOSP OF PHILADELPHIA · PI ERIC D MARSH, ROBERT Thomas SCHULTZ · 2021 to 2026
$9.2M
Novel bioinformatics methods to detect DNA and RNA modifications using Nanopore long-read sequencingR01HG013359 · NHGRI · CHILDREN'S HOSP OF PHILADELPHIA · PI Kai Wang · 2023 to 2026
$2.8M
NHGRI NIH HHS R01 HG013359NICHD NIH HHS P50 HD105354
6 · The paper itself

Abstract

Allele-specific analysis from RNA-seq is a powerful approach to characterize

Indexed as

allele-specific expressionallele-specific transcript usageexpectation-maximizationhaplotype phasinglong-read sequencingsingle-cell RNA-seq

Identifiers

PMID42146353
PMCPMC13174648

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.