Evidence map›Paper›PMID 42146677›Full record

ArticlebioRxiv : the preprint server for biology2026

Lymphatic egress recycles tumor-experienced effector CD8 T cells to sustain immune surveillance.

Ines Delclaux, Katherine S Ventre, Naomi R Besson, Tara Muijlwijk, Milad Ibrahim, Guanning Wang, Taylor A Heim, Maria M Steele, Alexander C Huang, Markus Schober and 2 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ines DelclauxRonald O. Perelman Department of Dermatology, NYU Grossman School of Medicine, NYU Langone Health, New York, NY, USA.ORCID 0009-0001-6420-2934
Katherine S VentreRonald O. Perelman Department of Dermatology, NYU Grossman School of Medicine, NYU Langone Health, New York, NY, USA.ORCID 0000-0002-7675-7355
Naomi R BessonRonald O. Perelman Department of Dermatology, NYU Grossman School of Medicine, NYU Langone Health, New York, NY, USA.ORCID 0009-0008-3548-913X
Tara MuijlwijkRonald O. Perelman Department of Dermatology, NYU Grossman School of Medicine, NYU Langone Health, New York, NY, USA.ORCID 0000-0003-3827-5694
Milad IbrahimRonald O. Perelman Department of Dermatology, NYU Grossman School of Medicine, NYU Langone Health, New York, NY, USA.ORCID 0009-0009-5783-4704
Guanning WangDivision of Hematology/Oncology, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.ORCID 0000-0001-5810-3270
Taylor A HeimRonald O. Perelman Department of Dermatology, NYU Grossman School of Medicine, NYU Langone Health, New York, NY, USA.ORCID 0000-0003-4128-5754
Maria M SteeleRonald O. Perelman Department of Dermatology, NYU Grossman School of Medicine, NYU Langone Health, New York, NY, USA.ORCID 0000-0003-0186-2633
Alexander C HuangDivision of Hematology/Oncology, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.ORCID 0000-0002-0099-0492
Markus SchoberRonald O. Perelman Department of Dermatology, NYU Grossman School of Medicine, NYU Langone Health, New York, NY, USA.ORCID 0000-0002-9122-2121
Iman OsmanRonald O. Perelman Department of Dermatology, NYU Grossman School of Medicine, NYU Langone Health, New York, NY, USA.ORCID 0000-0002-1472-1971
Amanda W LundRonald O. Perelman Department of Dermatology, NYU Grossman School of Medicine, NYU Langone Health, New York, NY, USA.ORCID 0000-0001-7389-9983

Funding

Vaccine FacilityP30CA016087 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI MARK Reid PHILIPS · 1985 to 2026
$83.1M
Project 3: The Evolving Role of Regional Lymph Nodes in Melanoma ProgressionU54CA263001 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Eva Hernando · 2022 to 2026
$11.6M
Training Program in Immunology and Inflammation.T32AI100853 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Susan Ruth Schwab · 2012 to 2026
$4.5M
Investigating T Cell Egress via Lymphatic Vessels in MelanomaR01CA238163 · NCI · OREGON HEALTH & SCIENCE UNIVERSITY · PI LUND, AMANDA W. · 2019 to 2023
$1.9M
Investigating T cell Circuits in the Lymphatic System During Melanoma ProgressionR01CA304163 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Amanda W. Lund · 2026 to 2026
$696k
The influence of lymph node metastasis on local and systemic anti-tumor immunityF30CA288142 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Katherine Ventre · 2024 to 2026
$127k
NCI NIH HHS F30 CA288142NCI NIH HHS P30 CA016087NCI NIH HHS R01 CA238163NCI NIH HHS R01 CA304163NCI NIH HHS U54 CA263001NIAID NIH HHS T32 AI100853
6 · The paper itself

Abstract

Successful anti-tumor immune surveillance depends on stem-like CD8

Indexed as

effector T cellsimmune checkpoint blockadelymphatic transportlymph node metastasismelanomastem-like T cellsT cell migrationtumor-draining lymph node

Identifiers

PMID42146677
PMCPMC13174550

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.