ArticleSAGE open medical case reports2026
Severe hypertriglyceridemia during pregnancy in a hypothyroid patient: A case report and literature review.
Article in SAGE open medical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 authors.
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Abstract
Normal pregnancy causes marked increases in lipids, but in women with underlying dyslipidaemia, this can lead to severe hypertriglyceridemia (triglyceride >1000 mg/dL) and acute pancreatitis. Coexisting conditions like diabetes and hypothyroidism further exacerbate this risk. We report a 34-year-old G2P1 woman at 32 weeks of gestation with type 2 diabetes and treated hypothyroidism who presented with acute pancreatitis and a serum triglyceride level of 33.8 mmol/L. Her management included therapeutic plasmapheresis, insulin infusion, and fenofibrate, followed by a planned elective caesarean section at 35 weeks, which resulted in the delivery of a healthy infant. This case highlights the critical need for vigilant lipid monitoring and a coordinated, multidisciplinary approach in high-risk pregnancies to prevent life-threatening complications and improve maternal and fetal outcomes.
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