ArticlePostepy dermatologii i alergologii2026
Prevalence of the most common types of high-risk HPV and p16
Article in Postepy dermatologii i alergologii, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: Human papillomavirus (HPV) is a leading sexually transmitted pathogen with oncogenic potential. While extensive data exist on HPV prevalence in men globally, Central and Eastern Europe remain understudied. Aim: This study investigates the prevalence of high-risk HPV types and p16 Material and methods: Post-mortem penile tissue samples from 52 men (aged 20-80) were collected from three anatomical sites: urethral meatus, coronal sulcus, and inner foreskin. HPV DNA was detected using SYBR Green-based qPCR and type-specific probe-based qPCR for HPV-6/11, -16, -18, -31, -33, -35, and -45. Expression of p16 Results: HPV DNA was identified in 13.5% of participants, with HPV-18 being the most prevalent type. One case exhibited co-infection with HPV-6/11 and HPV-16. Viral DNA copy numbers varied widely (1-2580/1000 cells). p16 Conclusions: The study confirms the presence of high-risk HPV infections among asymptomatic Polish men and suggests low oncogenic activity based on p16
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