Evidence map›Paper›PMID 42148709›Full record

ReviewEuropean journal of clinical investigation2026

Practical Recommendations for Anticoagulation in Patients With Atrial Fibrillation.

Nicolas Johner, Baris Gencer

Abstract readReview
In one paragraph

Review in European journal of clinical investigation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Nicolas JohnerCardiology Division, Geneva University Hospitals, Geneva, Switzerland.ORCID https://orcid.org/0000-0001-8236-1165
Baris GencerCardiology Division, Geneva University Hospitals, Geneva, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe lifetime risk of stroke among non-anticoagulated patients with atrial fibrillation (AF) approximates 1 in 3. Oral anticoagulation (OAC) reduces stroke and systemic embolism by at least two thirds and mortality by one fourth.

methodsThe present narrative review summarizes current evidence and practical recommendations on OAC in AF and highlights recent advances and remaining gaps in knowledge.

resultsThe threshold for net clinical benefit of OAC is met when stroke risk exceeds 1%-2% per year, typically corresponding to ≥ 1 traditional stroke risk factor (CHA

conclusionOAC is the cornerstone of thromboembolism prevention in AF, but knowledge gaps remain, including on risk stratification, device-detected AF, trigger-induced AF, cardioversion, OAC resumption after major bleeding, and potential safety of OAC discontinuation after successful catheter ablation or left atrial appendage occlusion.

Indexed as

AnticoagulantsAtrial FibrillationStrokeAdministration, OralHemorrhageHumansLeft Atrial Appendage ClosurePlatelet Aggregation InhibitorsPractice Guidelines as TopicRisk FactorsVitamin KAnticoagulantsPlatelet Aggregation InhibitorsVitamin Kanticoagulationatrial fibrillationbleedingdirect oral anticoagulantstrokethromboembolismvitamin K antagonist

Identifiers

PMID42148709
PMCPMC13182686

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.