Evidence map›Paper›PMID 42149248›Full record

Trial reportIntensive care medicine2026

Effects of out-of-bed armchair positioning on oxygenation in spontaneously breathing ICU patients receiving respiratory support: a randomized controlled trial.

Guillaume Fossat, Lucie Muller, Aline Seguin, Armelle Mathonnet, Séverine Pinos, Toufik Kamel, François Barbier, Céline Loiseau, Marion Guemann, Léa Courtes and 4 more

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Intensive care medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04446559 (Effect of " Sitting in a Chair " Versus " Conventional Semi-recumbent In-bed Position " on the Oxygenation Level for ICU Non-sedated Patients), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04446559 nacompletednot on this map

Effect of " Sitting in a Chair " Versus " Conventional Semi-recumbent In-bed Position " on the Oxygenation Level for ICU Non-sedated Patients

TypeinterventionalSponsorCentre Hospitalier Régional d'OrléansRan2020 to 2024Enrolled284ConditionsICU PatientArmsSitting in chair position
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Guillaume FossatMedical Intensive Care Unit Department, Orleans University Hospital, Orleans, France. guillaume.fossat@chu-orleans.fr.ORCID http://orcid.org/0000-0002-4879-1484
Lucie MullerMedical Intensive Care Unit Department, Orleans University Hospital, Orleans, France.
Aline SeguinMedical Intensive Care Unit Department, Orleans University Hospital, Orleans, France.
Armelle MathonnetMedical Intensive Care Unit Department, Orleans University Hospital, Orleans, France.
Séverine PinosMedical Intensive Care Unit Department, Orleans University Hospital, Orleans, France.
Toufik KamelMedical Intensive Care Unit Department, Orleans University Hospital, Orleans, France.
François BarbierMedical Intensive Care Unit Department, Orleans University Hospital, Orleans, France.
Céline LoiseauMedical Intensive Care Unit Department, Orleans University Hospital, Orleans, France.
Marion GuemannMedical Intensive Care Unit Department, Orleans University Hospital, Orleans, France.
Léa CourtesMedical Intensive Care Unit Department, Orleans University Hospital, Orleans, France.
Cécile FossatMedical Intensive Care Unit Department, Orleans University Hospital, Orleans, France.
Grégoire MullerMedical Intensive Care Unit Department, Orleans University Hospital, Orleans, France.
Mai-Anh NayMedical Intensive Care Unit Department, Orleans University Hospital, Orleans, France.
Thierry BoulainMedical Intensive Care Unit Department, Orleans University Hospital, Orleans, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeComparing the effects of an out-of-bed armchair position versus an in-bed semi-recumbent position on oxygenation in spontaneously breathing intensive care unit (ICU) patients, receiving respiratory support is a common practice with limited supported evidence.

methodsA single-center randomized controlled trial in spontaneously breathing adult ICU patients receiving invasive pressure support ventilation, high-flow nasal oxygen, or non-invasive ventilation. Patients were assigned to armchair or semi-recumbent in-bed positioning for 3 h. Arterial blood gasses were obtained immediately before and after positioning. PaO

results284 patients were randomized (146 and 138 in the armchair and bed groups, respectively). Baseline P/F ratios did not differ between groups. A significant interaction between group and time was observed (p = 0.002). In the armchair group, the P/F ratio increased by 13 mm Hg (95% CI 1-24), whereas it decreased by 13 mm Hg (95% CI - 25 to - 1) in the bed group. The post-positioning marginal mean P/F ratio was higher in the armchair group (241 mm Hg, 95% CI 214-268) than in the bed group (206 mm Hg, 95% CI 179-233; p = 0.004). No serious adverse events occurred. Minor adverse events were more frequent in the armchair group but had minimal impact on positioning duration.

conclusionIn spontaneously breathing ICU patients receiving respiratory support, out-of-bed armchair positioning was associated with higher oxygenation after 3 h than remaining in a semi-recumbent position, with no serious adverse events observed. CLINICALTRIALS: GOV-IDENTIFIER: NCT04446559.

Indexed as

Patient PositioningAgedBlood Gas AnalysisFemaleHumansIntensive Care UnitsMaleMiddle AgedOxygenOxygen Inhalation TherapyOxygenArmchair positionHigh-flow nasal oxygenIntensive care unitMechanical ventilationOxygenationSemi-recumbent

Identifiers

PMID42149248
PMCPMC13269415

What Socratic holds

Textmetadata
LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.