Evidence mapPaperPMID 42150824Full record

Trial reportBMJ open2026

Blended adapted sailing therapy with telerehabilitation for rare skeletal disorders: protocol for a pilot randomised controlled feasibility trial in Italy (PaS2-EXTEND).

Manila Boarini, Federico Banchelli, Davide Scognamiglio, Giuseppina Mariagrazia Farella, Daniela Platano, Serena Rizzo, Ugo Cavina, Giulia Rogati, Roberto Ramaglia Amadasi, Giacomo Villa and 7 more

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMJ open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07102875 (Pilot Study "Ready to Sail 2"), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07102875 nacompletednot on this map

Pilot Study "Ready to Sail 2": Evaluation of the Feasibility and Safety of Sail-Assisted Telerehabilitation in Patients With Rare Skeletal Diseases - Assessment of Motor, Psychosocial, and Quality of Life Outcomes

TypeinterventionalSponsorIstituto Ortopedico RizzoliRan2025 to 2026Enrolled24ConditionsRare Bone DisordersArmsSailing Intervention Plus Home-Based Telerehabilitation, Home-Based Telerehabilitation
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Manila BoariniDepartment of Rare Skeletal Disorders, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy manila.boarini@ior.it.ORCID http://orcid.org/0000-0002-9156-1772
Federico BanchelliDepartment of Rare Skeletal Disorders, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
Davide ScognamiglioPhysics and Astronomy Department (DIFA), Alma Mater Studiorum University, Bologna, Italy.
Giuseppina Mariagrazia FarellaPhysical Medicine and Rehabilitation Unit 1, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.ORCID http://orcid.org/0000-0002-3153-3737
Daniela PlatanoPhysical Medicine and Rehabilitation Unit 1, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
Serena RizzoPhysical Medicine and Rehabilitation Unit, Rizzoli-Sicilia Department, IRCCS Istituto Ortopedico Rizzoli, Palermo, Italy.
Ugo CavinaIndependent Practitioner, Bologna, Italy.
Giulia RogatiMovement Analysis Laboratory, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
Roberto Ramaglia AmadasiMovement Analysis Laboratory, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
Giacomo VillaEuleria srl Società Benefit, Rovereto (Trento), Italy.
Alberto LeardiniMovement Analysis Laboratory, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
Lisa BertiPhysical Medicine and Rehabilitation Unit 1, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
Silvana SartiniPhysical Medicine and Rehabilitation Unit, Rizzoli-Sicilia Department, IRCCS Istituto Ortopedico Rizzoli, Palermo, Italy.
Luciano MagnanelliLega Navale Italiana, Roma, Italy.
Alessandra LocatelliMinistro per le Disabilità, Roma, Italy.
Annalisa Maddalena ScopinaroUNIAMO-Federazione Italiana Malattie Rare, Rome, Italy.
Luca SangiorgiDepartment of Rare Skeletal Disorders, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionRare skeletal disorders (RSDs) cause lifelong functional impairment, chronic pain and reduced quality of life. Evidence-based rehabilitation strategies remain underdeveloped, particularly for adolescents and young adults. We previously demonstrated preliminary feasibility of a 5-day adapted sailing intervention but observed benefit attenuation at 3-month follow-up. This pilot trial evaluates feasibility, acceptability and safety of intensive adapted sailing therapy followed by home-based telerehabilitation maintenance versus telerehabilitation alone. METHODS AND ANALYSIS: This is a prospective, randomised, assessor-blinded, parallel two-arm pilot feasibility trial. 24 participants aged 12-30 years with confirmed RSDs will randomise with a 1:1 allocation ratio to: (1) 5-day adapted sailing therapy followed by 3-month telerehabilitation (n=12) or (2) 3-month telerehabilitation alone (n=12). Primary outcomes assess feasibility through recruitment efficiency (≥80% eligible patients enrolled), intervention adherence (≥75% sessions completed), participant retention (≥80% at 6-month follow-up), and safety (zero serious adverse events attributable to interventions). Secondary outcomes include sensor-based motor function (balance, gait, upper extremity mobility via inertial measurement units) and patient-reported outcomes (health-related quality of life, functional capacity, kinesiophobia, pain), measured at baseline, 3-month and 6-month follow-up. Exploratory analyses will estimate preliminary between-group effect sizes. Statistical analysis uses intention-to-treat principles with linear mixed-effects models. ETHICS AND DISSEMINATION: The study received approval from the Area Vasta Emilia Centro Ethics Committee (363/2025/Sper/IOR) on 7 July 2025. The study is ongoing, and data collection is expected to be completed by March 2026. Results will be disseminated through peer-reviewed open-access publications, conference presentations, patient organisation partnerships and plain-language summaries. TRIAL REGISTRATION NUMBER: NCT07102875.

Indexed as

Bone DiseasesExercise TherapyAdolescentAdultChildFeasibility StudiesFemaleHumansItalyKinesiophobiaMalePilot ProjectsProspective StudiesQuality of LifeResearch DesignTelerehabilitationBone diseasesFeasibility StudiesPatient Reported Outcome MeasuresRandomized Controlled TrialRare DiseasesWearable Devices

Identifiers

PMID42150824
PMCPMC13185042

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.