Evidence mapPaperPMID 42152113Full record

ReviewJournal of biological engineering2026

Advanced biomimetic nanomedicines for cell-based therapeutics: prospects and challenges.

Ying Wang, Liangliang Zhao, Ying Zou, Lili Nie

Abstract readReview
In one paragraph

Review in Journal of biological engineering, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ying WangDepartment of Ophthalmology, The Second Hospital of Jilin University, Changchun, 130000, China.
Liangliang ZhaoDepartment of Ophthalmology, The Second Hospital of Jilin University, Changchun, 130000, China.
Ying ZouDepartment of Ophthalmology, The Second Hospital of Jilin University, Changchun, 130000, China.
Lili NieDepartment of Ophthalmology, The Second Hospital of Jilin University, Changchun, 130000, China. niell@jlu.edu.cn.

Funding

Jilin Province Tianhua Health Charity Foundation J2024JKJ006
6 · The paper itself

Abstract

Advanced biomimetic nanomedicines offer cell-based therapeutics to mimic biological behaviors for improved targeting, immune evasion, and integration with living cells. This review critically examines recent innovations in biomimetic nanocarriers especially leveraging from cell membranes, membrane proteins, or native cellular structures to support cell therapies. These systems aid in prolonging circulation, reducing immunogenicity, and directing therapeutic cells to disease sites. Membrane-coated nanoparticles, metal-phenolic network-based nanovaccines, and stem-cell-membrane-coated carriers have therapeutic potential but challenges of manufacturing, scalability, quality control, in vivo stability, and regulatory barriers are present. To overcome these challenges, substituted hybrid membrane formulations, bio-responsive release mechanisms, and modular design are adopted. This review aims to guide future research toward clinical viable biomimetic nanomedicines for cell-based therapies.

Indexed as

Biomimetic nanomedicineCell-based therapeuticsDrug delivery systemsImmune cell-targeted nanomedicine

Identifiers

PMID42152113
PMCPMC13352753

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.