Evidence map›Paper›PMID 42152697›Full record

ArticleAnnals of medicine2026

Ankle-brachial index rather than brachial-ankle pulse wave velocity is associated with cognitive function in older adults undergoing incident hemodialysis: a multicentre cross-sectional study.

Kai Zheng, Chuanjun Huang, Yue Wang, Yahui Wu, Jiangling Guo, Cheng Chen, Yizhi Liu, Cheng Lin, Li Qin, Hailong Li and 5 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

15 authors.

Kai ZhengDepartment of Rehabilitation Medicine, Shanghai University of Medicine and Health Sciences Affiliated Zhoupu Hospital, Shanghai, China.
Chuanjun HuangDepartment of Rehabilitation Medicine, Shanghai University of Medicine and Health Sciences Affiliated Zhoupu Hospital, Shanghai, China.
Yue WangDepartment of Rehabilitation Medicine, Shanghai University of Medicine and Health Sciences Affiliated Zhoupu Hospital, Shanghai, China.
Yahui WuDepartment of Rehabilitation Medicine, Shanghai University of Medicine and Health Sciences Affiliated Zhoupu Hospital, Shanghai, China.
Jiangling GuoDepartment of Rehabilitation Medicine, Shanghai University of Medicine and Health Sciences Affiliated Zhoupu Hospital, Shanghai, China.
Cheng ChenDepartment of Rehabilitation Medicine, Shanghai University of Medicine and Health Sciences Affiliated Zhoupu Hospital, Shanghai, China.
Yizhi LiuDepartment of Rehabilitation Medicine, Shanghai University of Medicine and Health Sciences Affiliated Zhoupu Hospital, Shanghai, China.
Cheng LinDepartment of Rehabilitation Medicine, School of Health, Fujian Medical University, Fuzhou, China.
Li QinJiading Subdistrict Community Health Center, Shanghai, China.
Hailong LiDepartment of Rehabilitation Medicine, Shanghai University of Medicine and Health Sciences Affiliated Zhoupu Hospital, Shanghai, China.
Lizhe WuDepartment of Rehabilitation Medicine, Shanghai University of Medicine and Health Sciences Affiliated Zhoupu Hospital, Shanghai, China.
Xinyang WangDepartment of Rehabilitation Medicine, Shanghai University of Medicine and Health Sciences Affiliated Zhoupu Hospital, Shanghai, China.
Shixing MengDepartment of Rehabilitation Medicine, Shanghai University of Medicine and Health Sciences Affiliated Zhoupu Hospital, Shanghai, China.
Peipei HanDepartment of Rehabilitation Medicine, Shanghai University of Medicine and Health Sciences Affiliated Zhoupu Hospital, Shanghai, China.
Qi GuoDepartment of Rehabilitation Medicine, Shanghai University of Medicine and Health Sciences Affiliated Zhoupu Hospital, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsHemodialysis (HD) patients frequently experience cognitive impairment, potentially linked to arterial stiffness. However, the correlation between specific arterial stiffness and cognitive performance in hemodialysis patients has not been confirmed. The aim of this study was to examine the association between cognitive impairment and arterial stiffness in HD patients.

methodsThis cross-sectional study included HD patients undergoing hemodialysis treatment from seven hemodialysis centers in China. We determined arterial stiffness by brachial-ankle pulse wave velocity (baPWV) and ankle-brachial index (ABI) and assessed participants' cognitive function using the Mini-Mental State Examination (MMSE).

resultsA total of 889 HD participants were enrolled, with a mean age of 61.4 years, 37.6% being female, a median HD duration of 43.7 months, and 16.4% exhibiting cognitive impairment. Compared with the group with normal cognitive function, patients with cognitive impairment had higher baPWV (21.1 ± 5.8 vs 19.3 ± 4.8) and lower ABI (1.06 ± 0.21 vs 1.13 ± 0.17) (

conclusionsLower ABI, which is indicative of blockage of blood vessels in the lower limbs, is associated with declining cognitive function in patients on hemodialysis. CLINICAL

trial registrationChiCTR1900027039.

Indexed as

Ankle Brachial IndexCognitionCognitive DysfunctionKidney Failure, ChronicPulse Wave AnalysisRenal DialysisVascular StiffnessAgedChinaCross-Sectional StudiesFemaleHumansMaleMiddle AgedArterial stiffnesschronic kidney diseasecognitive functionhemodialysis

Identifiers

PMID42152697
PMCPMC13188536

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.