Evidence map›Paper›PMID 42153739›Full record

ArticleJournal of virology2026

Identification and characterization of novel chikungunya virus polymerase inhibitors.

Peiqi Yin, Ryan Boyce, Sainan Wang, Michael Sirrine, Alexander Leach, Dillon Chu, Dariia Vyshenska, Zafer Sahin, Jenny Wong, Tahirah Moore and 8 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of virology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors.

Peiqi Yin *Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York, USA.ORCID 0000-0003-0482-7825
Ryan Boyce *Center for Translational Antiviral Research, Institute for Biomedical Sciences, Georgia State University, Atlanta, Georgia, USA.
Sainan WangInstitute of Bioengineering, University of Tartu, Tartu, Estonia.
Michael SirrineCenter for Translational Antiviral Research, Institute for Biomedical Sciences, Georgia State University, Atlanta, Georgia, USA.
Alexander LeachCenter for Translational Antiviral Research, Institute for Biomedical Sciences, Georgia State University, Atlanta, Georgia, USA.
Dillon ChuCenter for Translational Antiviral Research, Institute for Biomedical Sciences, Georgia State University, Atlanta, Georgia, USA.
Dariia VyshenskaVirology Division, Department of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington, USA.
Zafer SahinDepartment of Chemistry, Emory University, Atlanta, Georgia, USA.
Jenny WongCenter for Translational Antiviral Research, Institute for Biomedical Sciences, Georgia State University, Atlanta, Georgia, USA.
Tahirah MooreCenter for Translational Antiviral Research, Institute for Biomedical Sciences, Georgia State University, Atlanta, Georgia, USA.
Devin Shane M LewisCenter for Translational Antiviral Research, Institute for Biomedical Sciences, Georgia State University, Atlanta, Georgia, USA.
Stephen C PellyDepartment of Chemistry, Emory University, Atlanta, Georgia, USA.
Dennis LiottaDepartment of Chemistry, Emory University, Atlanta, Georgia, USA.ORCID 0000-0002-7736-7113
Andres MeritsInstitute of Bioengineering, University of Tartu, Tartu, Estonia.ORCID 0000-0001-8193-0071
Alexander L GreningerVirology Division, Department of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington, USA.ORCID 0000-0002-7443-0527
Richard K PlemperCenter for Translational Antiviral Research, Institute for Biomedical Sciences, Georgia State University, Atlanta, Georgia, USA.ORCID 0000-0003-2034-2107
Margaret KielianDepartment of Cell Biology, Albert Einstein College of Medicine, Bronx, New York, USA.ORCID 0000-0002-7395-4791
Robert M CoxCenter for Translational Antiviral Research, Institute for Biomedical Sciences, Georgia State University, Atlanta, Georgia, USA.ORCID 0000-0003-0620-1674

Funding

Project 6 - Development of Antivirals against AlphavirusesU19AI171403 · NIAID · EMORY UNIVERSITY · PI George Robert Painter, Richard K. Plemper · 2022 to 2026
$59.7M
NIAID NIH HHS U19 AI171403
6 · The paper itself

Abstract

Chikungunya virus (CHIKV) and other alphaviruses in the

Indexed as

Antiviral AgentsChikungunya virusEnzyme InhibitorsRNA-Dependent RNA PolymeraseViral Nonstructural ProteinsAnimalsCell LineChikungunya FeverDrug Resistance, ViralHigh-Throughput Screening AssaysHumansMolecular Docking SimulationVirus ReplicationAntiviral AgentsEnzyme InhibitorsRNA-Dependent RNA PolymeraseViral Nonstructural ProteinsantiviralchikungunyansP4 inhibitor

Identifiers

PMID42153739
PMCPMC13288994

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.