Evidence map›Paper›PMID 42156813›Full record

ArticleScientific reports2026

Comprehensive macroscopic living anatomy of the swine heart: comparative visual approach with virtual dissection.

Kimberly P Rios, Antony M Moussa, Hayley A Rios, Mark Rimmer, Yuichiro Miyazaki, Daisetsu Aoyama, Rami N Aladham, Lily G Defelice, Peter Hanna, Justin H Hayase and 5 more

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Kimberly P RiosDavid Geffen School of Medicine, University of California Los Angeles (UCLA), Los Angeles, CA, USA.
Antony M MoussaDavid Geffen School of Medicine, University of California Los Angeles (UCLA), Los Angeles, CA, USA.
Hayley A RiosDavid Geffen School of Medicine, University of California Los Angeles (UCLA), Los Angeles, CA, USA.
Mark RimmerDavid Geffen School of Medicine, University of California Los Angeles (UCLA), Los Angeles, CA, USA.
Yuichiro MiyazakiDavid Geffen School of Medicine, University of California Los Angeles (UCLA), Los Angeles, CA, USA.
Daisetsu AoyamaDavid Geffen School of Medicine, University of California Los Angeles (UCLA), Los Angeles, CA, USA.
Rami N AladhamDavid Geffen School of Medicine, University of California Los Angeles (UCLA), Los Angeles, CA, USA.
Lily G DefeliceDavid Geffen School of Medicine, University of California Los Angeles (UCLA), Los Angeles, CA, USA.
Peter HannaDavid Geffen School of Medicine, University of California Los Angeles (UCLA), Los Angeles, CA, USA.
Justin H HayaseDavid Geffen School of Medicine, University of California Los Angeles (UCLA), Los Angeles, CA, USA.
Wei-Hsin ChungDivision of Cardiology, Department of Internal Medicine, Taichung municipal geriatric rehabilitation general hospital, Taichung, Taiwan.
Shili XuDepartment of Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
Olujimi A AjijolaDavid Geffen School of Medicine, University of California Los Angeles (UCLA), Los Angeles, CA, USA.
Kalyanam ShivkumarDavid Geffen School of Medicine, University of California Los Angeles (UCLA), Los Angeles, CA, USA.
Shumpei MoriDavid Geffen School of Medicine, University of California Los Angeles (UCLA), Los Angeles, CA, USA. smori@mednet.ucla.edu.

Funding

Neural Control of Myocardial Excitability at the Nerve Myocyte InterfaceP01HL164311 · UNIVERSITY OF CALIFORNIA LOS ANGELES · 2025 to 2025
$2.3M
Artificial Intelligence for Improved Breast Cancer Screening Accuracy: External Validation, Refinement, and Clinical TranslationR37CA240403 · NCI · UNIVERSITY OF WASHINGTON · 2022 to 2025
$2.1M
Cultivating Interest in Research Careers (CIRC)R25HL161609 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · 2023 to 2025
$386k
Leducq Foundation Translational Network Award 23CVD04NCI NIH HHS R37 CA240403NHLBI NIH HHS P01 HL164311NHLBI NIH HHS R25 HL161609
6 · The paper itself

Abstract

Swine is one of the major large animal species used in translational research. Extensive knowledge has been accumulated on the normal anatomy of the swine heart, highlighting its similarities with the human heart, including its size and coronary arterial system. However, when these hearts are compared three-dimensionally as they lie on each thorax without distortion, remarkable differences are recognized beyond already known similarities. Those differences include, but are not limited to, the cardiac axis, aortic axis, aortic arch plane, aortic arch/pulmonary trunk relationship, atrial appendages extent, pulmonary arteries/veins/trachea/bronchi relationship, left azygos vein drainage, coronary arterial orifices relationship, fossa ovalis/aortic root relationship, and ventricular trabeculations features. In addition to conventional and rough recognition of similarities between the swine and human hearts, detailed knowledge of differences in the living anatomy of the swine and human hearts is especially fundamental for conducting effective in vivo experiments, including fluoroscopic procedures and survival studies with surgical intervention. Also, this knowledge is useful for discussing the feasibility and limitations of applying the insights obtained from the swine heart study to the human heart. Thus, we herein demonstrate comprehensive macroscopic living anatomy of the swine heart compared with that of the human heart using cardiac computed tomographic datasets obtained from live swine, as well as datasets from recovered swine hearts after pressure-perfusion and fixation to maintain their physiological, non-distorted anatomy.

Indexed as

HeartAnimalsCoronary VesselsDissectionHumansImaging, Three-DimensionalSwineComparative anatomyComputed tomographyHeartSwineVirtual dissection

Identifiers

PMID42156813
PMCPMC13381882

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.