Evidence map›Paper›PMID 42157913›Full record

ReviewCurrent genomics2025

The Bacterial Role in the Progression of Breast Cancer through Mechanism of Gene Action: Future Prospects with Existing Studies.

Yasir Nawaz, Saba Munir, Sidra Aslam, Fizza Rimal Butt, Fouzia Tanvir, Basit Nawaz, Kazam Bashir, Rikza Tahreem

Abstract readReview
In one paragraph

Review in Current genomics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yasir NawazJiangsu Key Laboratory for Microbes and Genomics, Department of Microbiology, School of Life Sciences, Nanjing Normal University, 1 Wenyuan Road, Nanjing 210023, China.
Saba MunirDepartment of Zoology, Faculty of Life Sciences, University of Okara, Okara, Pakistan.
Sidra AslamDepartment of Biotechnology, Faculty of Sciences, University of Sialkot, Sialkot, Pakistan.
Fizza Rimal ButtDepartment of Biotechnology, Faculty of Sciences, University of Sialkot, Sialkot, Pakistan.
Fouzia TanvirDepartment of Zoology, Faculty of Life Sciences, University of Okara, Okara, Pakistan.
Basit NawazDepartment of Chemistry, University of Agriculture Faisalabad, Faisalabad, Pakistan.
Kazam BashirDepartment of Chemistry, University of Agriculture Faisalabad, Faisalabad, Pakistan.
Rikza TahreemDepartment of Zoology, Faculty of Life Sciences, University of Okara, Okara, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Breast cancer is the main cause of death for women, even with major improvements in treatment. Through processes like DNA damage, estrogen metabolism, and immunological regulation, bacterial populations have been shown to have an impact on breast cancer development in recent studies. Objectives: This review aimed to examine and evaluate current research on the involvement of bacteria in breast cancer progression, with an emphasis on gene action mechanisms and potential future treatments targeting the microbiome. Methods: A thorough literature analysis was carried out to identify pertinent research published between 1989-2024 across various databases, including PubMed, Google Scholar, Google, and Scopus. Results: Bacterial dysbiosis in the gut and breast tissue contributes to the progression of breast cancer through different pathways. Double-strand breaks in DNA are linked to various bacteria, like Conclusion: Bacteria contribute significantly to the development of breast cancer through gene-level processes. Probiotics, immunomodulatory techniques, and microbiome-targeted treatments are potential future developments that could improve therapy effectiveness and reduce resistance.

Indexed as

bacterial roleBreast cancercancer managementgene mechanismmicrobiota

Identifiers

PMID42157913
PMCPMC13154230

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.