ArticleInternational journal of biological sciences2026
Piezo1 in hypertrophic chondrocytes regulates osteoclastogenesis in endochondral ossification.
Article in International journal of biological sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- The developmental remodeling front: resorptive cell-vascular coupling at the chondro-osseous junction.Frontiers in cell and developmental biology · 2026Review
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Authors and funding
11 authors.
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Abstract
Ion channels of the Piezo family are key mechanosensors in diverse tissues, including bone. Recent studies have demonstrated that Piezo1 in differentiating chondrocytes is critical for endochondral ossification during bone development and regeneration. During endochondral ossification, chondrocytes undergo hypertrophy prior to apoptosis or transdifferentiation into bone-forming osteoblasts, thereby significantly contributing to new bone formation. Here, we investigated the specific role of Piezo1 in hypertrophic chondrocytes using a mouse model with conditional
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Registered trials
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