Evidence map›Paper›PMID 42160788›Full record

ArticleHormones and behavior2026

Sex-specific regulation of social play in juvenile rats by oxytocin neurons in the hypothalamus and oxytocin signaling in the nucleus accumbens.

Samantha M Bowden, Kira D Becker, Anna Luxhoj, Valery Grinevich, Jessica D A Lee, Alexa H Veenema

Abstract read
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In one paragraph

Article in Hormones and behavior, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Samantha M BowdenNeurobiology of Social Behavior Laboratory, Department of Psychology and Neuroscience Program, Michigan State University, East Lansing, MI, 48824, United States of America. Electronic address: bowdensa@msu.edu.
Kira D BeckerNeurobiology of Social Behavior Laboratory, Department of Psychology and Neuroscience Program, Michigan State University, East Lansing, MI, 48824, United States of America.
Anna LuxhojNeurobiology of Social Behavior Laboratory, Department of Psychology and Neuroscience Program, Michigan State University, East Lansing, MI, 48824, United States of America.
Valery GrinevichDepartment of Neuropeptide Research in Psychiatry, Central Institute of Mental Health, University of Heidelberg, Mannheim, Germany.
Jessica D A LeeNeurobiology of Social Behavior Laboratory, Department of Psychology and Neuroscience Program, Michigan State University, East Lansing, MI, 48824, United States of America.
Alexa H VeenemaNeurobiology of Social Behavior Laboratory, Department of Psychology and Neuroscience Program, Michigan State University, East Lansing, MI, 48824, United States of America.

Funding

Sex-specific regulation of social playR01MH102456 · NIMH · MICHIGAN STATE UNIVERSITY · PI VEENEMA, ALEXANDRA H. · 2014 to 2018
$1.7M
NIMH NIH HHS R01 MH102456
6 · The paper itself

Abstract

Social play is a rewarding behavior shown across juvenile mammalian species and is important for the development of social competency throughout the lifespan. The neuropeptide oxytocin (OXT) regulates various social behaviors and is being used in clinical trials to improve social functioning. However, the role of OXT in juvenile social play is largely unknown. To address this gap, we determined the involvement of hypothalamic OXT-producing neurons in the supraoptic nucleus (SON) and paraventricular nucleus (PVN), PVN

Indexed as

HypothalamusNeuronsNucleus AccumbensOxytocinPlay and PlaythingsSocial BehaviorAnimalsFemaleMaleParaventricular Hypothalamic NucleusRatsRats, Sprague-DawleyReceptors, OxytocinSex CharacteristicsSignal TransductionSupraoptic NucleusOxytocinReceptors, OxytocinNucleus accumbensOxytocinParaventricular nucleusSex differencesSocial behaviorSocial play

Identifiers

PMID42160788
PMCPMC13325120

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.