Evidence map›Paper›PMID 42164490›Full record

ReviewFrontiers in immunology2026

Cell death in uveitis: pyroptosis, ferroptosis, apoptosis, and beyond.

Jianxin Liu, Liming Mao, Guoqing Chen, Liang Zou, Yi Shi, Lingxi Jiang, Jiayu Meng

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jianxin LiuGenetic Diseases Key Laboratory of Sichuan Province, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.
Liming MaoDepartment of Immunology, School of Medicine, Nantong University, Nantong, Jiangsu, China.
Guoqing ChenGenetic Diseases Key Laboratory of Sichuan Province, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.
Liang ZouSchool of Food and Biological Engineering, Chengdu University, Chengdu, China.
Yi ShiDepartment of Ophthalmology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.
Lingxi JiangGenetic Diseases Key Laboratory of Sichuan Province, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.
Jiayu MengGenetic Diseases Key Laboratory of Sichuan Province, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Uveitis is a group of diseases characterized by intraocular inflammation, closely associated with infectious, autoimmune, genetic, or environmental factors. Cell death, a critical biological process involved in development, the maintenance of homeostasis, and the pathogenesis of disease, serves as both a trigger for inflammation and a direct cause of tissue damage in uveitis. This review comprehensively summarized the roles of various forms of cell death in the pathogenesis of uveitis, providing a novel theoretical framework for advancing the understanding of its underlying mechanisms, subtype classification, prognosis evaluation, and biomarker development. Furthermore, we analyzed the efficacy and potential applications of therapeutic strategies targeting these cell death pathways, thereby laying a foundation for exploring personalized combination therapies for uveitis.

Indexed as

ApoptosisCell DeathFerroptosisPyroptosisUveitisAnimalsHumansapoptosisautophagic cell deathcell deathferroptosisnecroptosisNETosispyroptosisuveitis

Identifiers

PMID42164490
PMCPMC13183624

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.