Evidence map›Paper›PMID 42166284›Full record

ArticleJournal of psychopathology and clinical science2026

The p factor and associations across partners, time, and generations: Commentary on Caspi et al. (2026).

Erik Pettersson

Abstract readComment
PubMed Publisher
In one paragraph

Article in Journal of psychopathology and clinical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Erik PetterssonKarolinska Institutet, Department of Medical Epidemiology and Biostatistics.ORCID 0000-0003-0149-9002

Funding

Brain FoundationSwedish Research CouncilSwedish Research Council for Health, Working Life and Welfare
6 · The paper itself

Abstract

Comments on the original article by Caspi et al. (see record 2026-80066-001). Drawing on both surveys and (primary and specialist care-assigned) register-based diagnoses, Caspi et al. displayed that the positive manifold among psychiatric conditions is present not only between individuals, but also across partners, time, and generations. To this impressive work, I add three comments. First, regarding intergenerational transdiagnostic transmission, our research group observed a similar pattern of results in a sample of three million Swedes linked to their parents, and that the results extended to school and labor market performance (Zhou et al., 2024). Second, regarding transdiagnostic patterns over time, Caspi et al. (2026) argued that most disorders eventually morph into different disorders. Third, although the observed transdiagnostic patterns across partners, time, and generations are consistent with an underlying p-factor, so are other models without a p-factor (Caspi & Moffitt, 2018). (PsycInfo Database Record (c) 2026 APA, all rights reserved).

Indexed as

Mental DisordersHumans

Identifiers

PMID42166284

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.