ReviewInternational journal of endocrinology and metabolism2026
The Association Between Cardiovascular Risk Factors and Emotional States: A Summary of the Tehran Lipid and Glucose Study.
Review in International journal of endocrinology and metabolism, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Context: The current study aimed to review the studies that investigated the association of cardiovascular risks and emotional states in men and women participating in the Tehran Lipid and Glucose Study (TLGS). Evidence Acquisition: A comprehensive search of PubMed, Scopus, and Web of Science was conducted to identify cross-sectional and prospective studies published through February 2026, based on predetermined inclusion and exclusion criteria. Cardiovascular risk factors were defined as weight status, blood pressure, and insulin resistance, while emotional states encompassed depression, anxiety, and stress. Given the heterogeneity in study designs and outcomes, the findings were synthesized narratively, and a meta-analysis was not performed. Results: Six eligible studies (four cross-sectional and two prospective) were included. Their findings indicated that hypertension and insulin resistance were associated with increased emotional distress, particularly among women with diagnosed hypertension. Long-term weight analyses showed that higher stress levels in males were associated with progression to overweight and obesity from childhood. Severe obesity was associated with greater mental distress in both sexes. Studies on obesity phenotypes indicated that higher anxiety and stress scores were observed among metabolically unhealthy obese women, a pattern also observed in metabolically unhealthy men regardless of weight status. Conclusions: Evidence from the TLGS indicated a sex-dependent association between cardiovascular risks and emotional states, with a significant association observed specifically in women.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.