ArticleJournal of gastrointestinal oncology2026
Impact of preoperative body weight on short-term and long-term prognosis after pancreatic resection for pancreatic ductal adenocarcinoma: a multicenter study.
Article in Journal of gastrointestinal oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
Background: The prognostic implications of preoperative body mass index (BMI) in patients undergoing curative-intent pancreatic resection for pancreatic ductal adenocarcinoma (PDAC) remain poorly characterized, with existing evidence demonstrating contradictory findings. This multicenter cohort study comprehensively analyzes the association between BMI stratification and both perioperative outcomes and long-term survival in PDAC patients receiving surgical intervention. Methods: Study participants were stratified into three predefined BMI strata: low-BMI group (BMI <18.5 kg/m Results: Multivariable analyses revealed that both low-BMI and high-BMI were associated with significantly elevated mortality [odds ratio (OR) 4.952, 95% confidence interval (CI): 1.238-19.799, P=0.02, and OR 3.911, 95% CI: 1.134-13.491, P=0.03] and overall morbidity (OR 2.008, 95% CI: 1.149-3.509, P=0.01, and OR 1.820, 95% CI: 1.191-2.783, P=0.006). In addition, multivariable Cox-regression analyses revealed that both preoperative low-BMI and high-BMI were independent predictors of OS [hazard ratio (HR) 1.410, 95% CI: 1.049-1.896, P=0.02 and HR 1.609, 95% CI: 1.274-2.034, P<0.001] and RFS (HR 1.395, 95% CI: 1.050-1.853, P=0.02 and HR 1.575, 95% CI: 1.249-1.987, P<0.001). Conclusions: Patients with low-BMI and high-BMI demonstrate a significantly worse prognosis compared to those with normal-BMI following pancreatic resection for PDAC.
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