Evidence map›Paper›PMID 42170122›Full record

ReviewCureus2026

Component-Level Effects of Enhanced Recovery After Surgery Protocols on Postoperative Outcomes Across Surgical Specialties: A Systematic Review.

Bilal Ahmad, Muhammad Bux, Ali Haider Bajwa, Basil Ahmed Ali Ali Elgohary, Alara Khan

Abstract readReview
In one paragraph

Review in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Bilal AhmadUrology, York and Scarborough Teaching Hospitals NHS Foundation Trust, York, GBR.
Muhammad BuxGeneral Surgery, Jinnah Postgraduate Medical Center, Karachi, PAK.
Ali Haider BajwaGeneral Surgery, Mymensingh Medical College, Mymensingh, BGD.
Basil Ahmed Ali Ali ElgoharyCardiothoracic Surgery, Ain Shams University, Cairo, EGY.
Alara KhanGeneral Surgery, Fatima Jinnah Medical University, Lahore, PAK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Enhanced recovery after surgery (ERAS) protocols have been widely adopted across surgical specialties to improve postoperative outcomes; however, the relative contribution of individual components within these multimodal pathways remains unclear. This systematic review aimed to evaluate the association between specific ERAS components and postoperative outcomes across diverse surgical settings. A comprehensive literature search was conducted in PubMed/MEDLINE, Scopus, and Web of Science for studies published between January 1, 2015, and December 31, 2025, in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 guidelines. Observational cohort studies assessing ERAS protocols with reported compliance or component-level data and relevant postoperative outcomes were included. Data extraction focused on study characteristics, ERAS components, compliance measures, and clinical outcomes, and risk of bias was assessed using the Newcastle-Ottawa Scale. Eight studies comprising 4,959 patients across colorectal, hepatobiliary, pancreatic, thoracic, gynecologic, gastric, and head and neck surgeries were included. Higher ERAS compliance was consistently associated with reduced postoperative complications and shorter length of stay, demonstrating a dose-response relationship in most studies. Component-level analyses identified early mobilization, early enteral nutrition, perioperative fluid optimization, minimization of invasive tubes and catheters, and multimodal analgesia as the most consistently beneficial interventions. The timing of implementation, particularly within the early postoperative period, emerged as a critical determinant of outcomes. However, heterogeneity across studies and findings from a large multicenter cohort suggest that partial or inconsistent ERAS implementation may not confer significant benefit. Overall, while adherence to ERAS protocols is associated with improved postoperative recovery, a subset of key components appears to drive these effects across surgical specialties. These findings support a targeted, component-focused approach to ERAS implementation, emphasizing early postoperative interventions and high-fidelity execution, particularly in settings where full protocol adherence may be challenging.

Indexed as

early enteral nutritionearly mobilizationenhanced recovery after surgeryerasfluid managementlength of staymultimodal analgesiaperioperative carepostoperative complicationspostoperative outcomes

Identifiers

PMID42170122
PMCPMC13189220

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.