Evidence map›Paper›PMID 42170270›Full record

ArticleTranslational lung cancer research2026

Air pollution, driver mutations, and survival in non-small cell lung cancer: insights from a high-altitude Hispanic cohort.

Mateo Tamayo, Nicolás Duque-Clavijo, Astrid Berena Herrera-López, Manuela Estrada-Schweineberg, Andres Felipe Bejarano, Juliana Pardo-Aljure, Laura Baldovino-Chiquillo, David Uscategui-López, Sebastián Dueñas-Hernández, María Paula Molina and 12 more

Abstract read
In one paragraph

Article in Translational lung cancer research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Breathing carcinogens: PMJournal of thoracic disease · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Mateo TamayoMedical Directorate, Fundación Santa Fe de Bogotá, Bogotá, Colombia.ORCID https://orcid.org/0009-0007-9764-3203
Nicolás Duque-ClavijoSchool of Medicine, Universidad de los Andes, Bogotá, Colombia.ORCID https://orcid.org/0009-0009-4553-5168
Astrid Berena Herrera-LópezSchool of Medicine, Universidad de los Andes, Bogotá, Colombia.ORCID https://orcid.org/0000-0002-7291-5985
Manuela Estrada-SchweinebergCancer Institute, Fundación Santa Fe de Bogotá, Bogotá, Colombia.ORCID https://orcid.org/0009-0001-2776-1331
Andres Felipe BejaranoCancer Institute, Fundación Santa Fe de Bogotá, Bogotá, Colombia.ORCID https://orcid.org/0009-0008-5344-9246
Juliana Pardo-AljureSchool of Medicine, Universidad de los Andes, Bogotá, Colombia.ORCID https://orcid.org/0009-0003-0830-5044
Laura Baldovino-ChiquilloSchool of Medicine, Universidad de los Andes, Bogotá, Colombia.ORCID https://orcid.org/0000-0003-3441-9371
David Uscategui-LópezSchool of Medicine, Universidad de los Andes, Bogotá, Colombia.ORCID https://orcid.org/0009-0000-0409-7450
Sebastián Dueñas-HernándezSchool of Medicine, Universidad de los Andes, Bogotá, Colombia.ORCID https://orcid.org/0009-0003-7770-3150
María Paula MolinaSchool of Medicine, Universidad de los Andes, Bogotá, Colombia.
María José GarcíaSchool of Medicine, Universidad de los Andes, Bogotá, Colombia.
Diana CañonSchool of Medicine, Universidad de los Andes, Bogotá, Colombia.ORCID https://orcid.org/0000-0002-2444-1738
Margarita BaldiónSchool of Medicine, Universidad de los Andes, Bogotá, Colombia.ORCID https://orcid.org/0000-0002-3785-2237
Sergio CruzPathology Department, Fundación Santa Fe de Bogotá, Bogotá, Colombia.
Luis Eduardo PinoBiomedical Engineering Department, Universidad de los Andes, Bogotá, Colombia.ORCID https://orcid.org/0000-0003-4475-7470
Henry VargasCancer Institute, Fundación Santa Fe de Bogotá, Bogotá, Colombia.
Javier SegoviaCancer Institute, Fundación Santa Fe de Bogotá, Bogotá, Colombia.ORCID https://orcid.org/0000-0001-8971-0911
Erick CantorCancer Institute, Fundación Santa Fe de Bogotá, Bogotá, Colombia.ORCID https://orcid.org/0000-0002-0920-219X
Omaira Valencia-EstupiñanPopulation Health Directorate, Fundación Santa Fe de Bogotá, Bogotá, Colombia.ORCID https://orcid.org/0000-0003-1617-1667
Olga L SarmientoSchool of Medicine, Universidad de los Andes, Bogotá, Colombia.ORCID https://orcid.org/0000-0002-9190-3568
Andrés F CardonaDirection of Research, Science and Education, Luis Carlos Sarmiento Angulo Cancer Treatment and Research Center - CTIC, Bogotá, Colombia.ORCID https://orcid.org/0000-0003-3525-4126
Beatriz WillsSchool of Medicine, Universidad de los Andes, Bogotá, Colombia.ORCID https://orcid.org/0000-0002-6837-3722

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Lung cancer remains a critical global health concern, with a substantial fraction arising in never-smokers. Air pollution-including particulate matter (PM Methods: A retrospective cohort study was conducted on 205 Hispanic patients diagnosed with NSCLC between 2015 and 2022 at a quaternary care hospital in Bogotá, Colombia. Lung cancer driver mutations [epidermal growth factor receptor mutations (EGFRm), anaplastic lymphoma kinase (ALK) rearrangement, and programmed death-ligand 1 (PD-L1) expression] were assessed by reverse transcription polymerase chain reaction and immunohistochemistry. The estimated individual-level exposure to air pollutants (PM Results: Mean annual exposure to PM2.5 (15.9 µg/m Conclusions: These results underscore the potential impact of air pollution on the molecular landscape and clinical outcomes of patients diagnosed with NSCLC, and they open new avenues for research in genetically admixed populations.

Indexed as

air pollutiondriver mutationsLatin Americalung cancer overall survival (OS)Non-small cell lung cancer (NSCLC)

Identifiers

PMID42170270
PMCPMC13186636

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.