Evidence map›Paper›PMID 42170746›Full record

ArticleEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin2026

Cross-reactive human antibody responses to H9N2 influenza virus, New York, United States, 2025.

Gagandeep Singh, Disha Bhavsar, Lucas M Ferreri, Jessica R Nardulli, Charles Gleason, Neko Lyttle, Yuexing Chen, Anice C Lowen, Viviana Simon, Florian Krammer

Abstract read
In one paragraph

Article in Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Gagandeep SinghCenter for Vaccine Research and Pandemic Preparedness (C-VaRPP), Icahn School of Medicine at Mount Sinai (ISMMS), New York, United States.
Disha BhavsarCenter for Vaccine Research and Pandemic Preparedness (C-VaRPP), Icahn School of Medicine at Mount Sinai (ISMMS), New York, United States.
Lucas M FerreriDepartment of Microbiology and Immunology, Emory University School of Medicine, Atlanta, United States.
Jessica R NardulliCenter for Vaccine Research and Pandemic Preparedness (C-VaRPP), Icahn School of Medicine at Mount Sinai (ISMMS), New York, United States.
Charles GleasonCenter for Vaccine Research and Pandemic Preparedness (C-VaRPP), Icahn School of Medicine at Mount Sinai (ISMMS), New York, United States.
Neko LyttleCenter for Vaccine Research and Pandemic Preparedness (C-VaRPP), Icahn School of Medicine at Mount Sinai (ISMMS), New York, United States.
Yuexing ChenCenter for Vaccine Research and Pandemic Preparedness (C-VaRPP), Icahn School of Medicine at Mount Sinai (ISMMS), New York, United States.
Anice C LowenDepartment of Microbiology and Immunology, Emory University School of Medicine, Atlanta, United States.
Viviana SimonDivision of Infectious Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai (ISMMS), New York, United States.
Florian KrammerIgnaz Semmelweis Institute, Interuniversity Institute for Infection Research, Medical University of Vienna, Vienna, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Understanding population immunity to emerging viruses is critical for risk assessment. We characterised antibody responses to avian influenza A(H9N2) viruses in 298 human sera from adults in New York City. We observed widespread cross-reactive H9-binding antibodies, albeit at lower levels (GMT = 371.3) than against seasonal H3 (GMT = 1,398.0), with low to undetectable haemagglutination inhibition and neutralising antibodies. In contrast, NA-binding and neuraminidase inhibition responses were moderate (GMT = 149.5 and 34.2) and comparable to those against human seasonal N2 (GMT = 259.0 and 42.2).

Indexed as

Antibodies, ViralInfluenza A Virus, H9N2 SubtypeInfluenza, HumanAdultAnimalsAntibodies, NeutralizingBirdsCross ReactionsHemagglutination Inhibition TestsHumansInfluenza in BirdsNeuraminidaseNew York CityAntibodies, NeutralizingAntibodies, ViralNeuraminidaseavian influenzaH9N2influenza A viruszoonoses

Identifiers

PMID42170746
PMCPMC13197736

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.