Evidence map›Paper›PMID 42176184›Full record

SynthesisAdvances in therapy2026

The Impact of Untreated Attention-Deficit/Hyperactivity Disorder on Motor Vehicle Accidents: A Systematic Review and Meta-Analysis.

Ann Childress, Hirah Malik, Jim Potenziano

Erratum issuedAbstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Advances in therapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Ann ChildressCenter for Psychiatry and Behavioral Medicine, Inc., 2851 N Tenaya Way, Suite 206, Las Vegas, NV, 89128, USA.
Hirah MalikTris Pharma, Inc., 2031 US-130, Monmouth Junction, NJ, 08852, USA.
Jim PotenzianoTris Pharma, Inc., 2031 US-130, Monmouth Junction, NJ, 08852, USA. jpotenziano@trispharma.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThis meta-analysis quantified the dangers of driving with untreated ADHD and compares consequences for untreated drivers with ADHD to those of better publicized accident risk factors.

methodsA systematic literature review and meta-analysis of published data was performed to determine the correlation between driving with untreated ADHD and motor vehicle accidents (MVAs). Separate analyses were performed for alcohol use and driving, excessive speed, cannabis use, sleepiness/fatigue, opioids/benzodiazepines, and cell phone use.

resultsFour studies showed significantly higher odds of an accident among untreated ADHD drivers versus the general population of drivers-a 93% increase [(significant pooled odds ratio (OR), 95% confidence interval (CI) for the overall effect, p < 0.001]. The odds of having an accident was increased by 85% in THC/cannabis users (significant pooled OR, 95% CI, p < 0.001); 162% increase in sleepy/tired drivers (significant pooled effect OR, 95% CI, p = 0.004); and 53% increase in opioid or benzodiazepine users (significant pooled OR, 95% CI, p < 0.001).

conclusionThis analysis found that MVAs occur significantly more frequently with drivers with untreated ADHD compared to the general population of drivers. Increasing awareness of accident risk among drivers with untreated ADHD and the positive impact of treating ADHD on driving highlights the importance of treating ADHD.

Indexed as

Accidents, TrafficAttention Deficit Disorder with HyperactivityAutomobile DrivingAlcohol DrinkingBenzodiazepinesCell Phone UseFatigueHumansRisk FactorsBenzodiazepinesAccidentsADHDAttention-deficit/hyperactivity disorderCrashesDriving

Identifiers

PMID42176184
PMCPMC13499775

What Socratic holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.