Evidence map›Paper›PMID 42176243›Full record

ReviewCurrent psychiatry reports2026

Management of Lithium in Pregnancy and Lactation: An Individualized Approach.

Hannah K Betcher, Alexandra Vydysh, Brittany D Ellington, Crystal T Clark

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current psychiatry reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hannah K BetcherDepartment of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA.
Alexandra VydyshDepartment of Pharmacology and Toxicology, University of Toronto, Toronto, ON, Canada.
Brittany D EllingtonWomen's College Hospital, Toronto, ON, Canada.
Crystal T ClarkDepartment of Psychiatry, University of Toronto, Toronto, ON, Canada. Crystal.clark@wchospital.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewBipolar disorder (BD) is a chronic illness that affects around 4% of the population, impacting women throughout their reproductive years. Times of hormonal change, such as peripartum, can be a particularly vulnerable period for individuals. There is a high risk of mood episodes during this time, and pharmacotherapy remains the primary treatment for individuals with BD. For many patients and clinicians, fears and misunderstandings around the use of lithium in pregnancy and lactation result in discontinuation of treatment or undertreatment. This review examines the data on lithium use in pregnancy and lactation, and focuses on optimizing management with an individualized approach. RECENT

findingsLithium is a reasonable treatment option throughout peripartum including during lactation, although dose adjustments and additional monitoring may be necessary. Patients with mood disorders who achieve stability on lithium and are planning for pregnancy can continue lithium and maintain emotional wellness, with an individualized approach to dosing and monitoring.

Indexed as

Antimanic AgentsBipolar DisorderLactationLithium CompoundsPregnancy ComplicationsBreast FeedingFemaleHumansPregnancyAntimanic AgentsLithium CompoundsLithium in breastfeedingLithium in lactationLithium in pregnancyPerinatal bipolar disorderPeripartum bipolar disorder

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.