Evidence map›Paper›PMID 42178549›Full record

ArticleBMC plant biology2026

GC-MS characterization and in vitro antimicrobial activity of essential oils from selected Lamiaceae species collected in Kashan, Iran.

Shahab Ojani, Mansureh Ghavam

Abstract read
In one paragraph

Article in BMC plant biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Shahab OjaniDepartment of Nature Engineering, Faculty of Natural Resources and Earth Sciences, University of Kashan, Kashan, Iran.
Mansureh GhavamDepartment of Nature Engineering, Faculty of Natural Resources and Earth Sciences, University of Kashan, Kashan, Iran. mghavam@kashanu.ac.ir.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infectious microorganisms are among the major factors that complicate skin and wound infections, highlighting the need for novel antimicrobial agents of natural origin. In this in vitro study, the essential oils (EOs) of four Lamiaceae species (Mentha longifolia (L.) L., Mentha spicata L., Salvia reuteriana Boiss., and Teucrium polium L.) collected from Kashan, Iran, were evaluated for their chemical composition and antimicrobial activity against selected standard microbial strains. The aerial parts were collected from three regions (Cheshme Shahsavaran, Nushabad, and Sefidshahr), and EOs were extracted using hydrodistillation with a Clevenger apparatus. Chemical constituents were analyzed by Gas chromatography-mass spectrometry (GC-MS). Antimicrobial activity was assessed using agar well diffusion and broth microdilution methods to determine inhibition zone diameter, minimum inhibitory concentration (MIC), and minimum bactericidal/fungicidal concentration (MBC/MFC) against Gram-positive bacteria Staphylococcus epidermidis (CIP 81.55) and Staphylococcus aureus (ATCC 29737); three Gram-negative bacteria, Klebsiella pneumoniae (ATCC 10031), Proteus mirabilis (ATCC 43071), and Pseudomonas aeruginosa (ATCC 27853); and one yeast strain, Candida albicans (ATCC 10231).The highest EO yield (2.37%) was obtained from M. spicata, while S. reuteriana showed the lowest yield (0.43%). GC-MS analysis identified pulegone (38.63%) in M. longifolia, carvone (50.47%) in M. spicata, α-pinene (18.92%) in T. polium, and n-hexyl benzoate (82.14%) in S. reuteriana. Among the tested samples, M. longifolia EOs showed the highest activity among the evaluated EOs, with a 10 mm inhibition zone against S. epidermidis and the lowest MIC value (250 µg/mL) against C. albicans. M. spicata EOs also demonstrated measurable in vitro activity against P. aeruginosa (MIC = 250 µg/mL). These findings provide preliminary experimental evidence that EOs from these native Lamiaceae species contain bioactive constituents with measurable in vitro antimicrobial activity. However, further mechanistic investigations and in vivo studies are necessary to clarify their biological relevance and potential applications.

Indexed as

Anti-Infective AgentsLamiaceaeOils, VolatileAnti-Bacterial AgentsGas Chromatography-Mass SpectrometryIranMicrobial Sensitivity TestsAnti-Bacterial AgentsAnti-Infective AgentsOils, VolatileChemical constituentsEssential Oils (EOs)LamiaceaeMinimum Inhibitory Concentration (MIC)Skin and wound infections

Identifiers

PMID42178549
PMCPMC13377729

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.