ArticleJournal of the American Heart Association2026
In-Hospital Improved Left Ventricular Ejection Fraction and Prognosis in Acute Heart Failure.
Article in Journal of the American Heart Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Improved Ejection Fraction in the Acute Heart Failure Setting: Cardiac Structure, Cardiac Function, or Extrinsic Factors?Journal of the American Heart Association · 2026Article
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Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe in-hospital trajectories of left ventricular ejection fraction (LVEF) in patients admitted for acute heart failure have been poorly investigated. We sought to assess the rate of heart failure with improved ejection fraction (HFimpEF) at discharge in acute heart failure, to identify predictors of HFimpEF and to evaluate the association of HFimpEF with outcome.
methodsWe retrospectively enrolled patients admitted for acute heart failure, with ≥2 in-hospital echocardiographic evaluations of LVEF and with LVEF ≤40% at admission. HFimpEF was defined as LVEF >40% at discharge, with an improvement in LVEF ≥10%. The primary end point was 1-year all-cause death. Trajectories of LVEF were also assessed at follow-up ambulatory visit at 1 year after discharge.
resultsThe overall population included 779 patients with LVEF ≤40% at admission; at discharge, 14.9% had HFimpEF. The independent predictors of HFimpEF were valvular heart disease (odds ratio, 3.460;
conclusionsIn patients with acute heart failure admitted with LVEF ≤40%, 15% had HFimpEF at predischarge reassessment. Valvular pathogenesis of heart failure with reduced ejection fraction, absent right ventricular dysfunction and less severe left ventricular remodeling were associated with higher likelihood of in-hospital HFimpEF. One-year and 5-year mortality risk was lower in patients with HFimpEF compared with patients with nonimproved LVEF.
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