ArticleFrontiers in public health2026
Alleviating psychosocial distress in drug-resistant tuberculosis: a pre-post study on telephone-delivered motivational interviewing.
Article in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: This pilot feasibility study aimed to evaluate the efficacy of a telephone-delivered motivational interviewing (MI) intervention in alleviating loneliness, depressive symptoms, and anxiety among patients with drug-resistant tuberculosis (DR-TB). Methods: Employing a single-group pre-post design, 74 DR-TB patients were recruited from the tuberculosis wards of Chengdu Public Health Clinical Medical Center between January and December 2021. Participants underwent a 12-week MI-based telephone intervention, with assessments at baseline (Week 0) and post-intervention (Week 16). Primary outcomes included changes in psychological measures using validated instruments: the University of California, Los Angeles Loneliness Scale (UCLA-LS), Self-Rating Depression Scale (SDS), and Hamilton Anxiety Rating Scale (HAMA). Secondary outcomes encompassed sleep quality, assessed by the Pittsburgh Sleep Quality Index (PSQI), and medication adherence, defined as a binary outcome based on pill count. Results: The intervention significantly reduced loneliness (UCLA-LS: 47.23 ± 10.14 → 40.23 ± 12.76, Conclusion: This pilot pre-post study provides preliminary evidence that telephone-delivered MI is associated with improved psychological outcomes in DR-TB patients. The findings support its promise as an accessible intervention, but the exploratory design necessitates further investigation through controlled trials to confirm efficacy and establish causal inference.
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