Evidence map›Paper›PMID 42180912›Full record

ArticleTranslational cancer research2026

Establishing the role of the neurotransmitter receptor-related gene

Leiyan Wei, Wu Zhu, Zhiqin Guo, Hong Zhang, Linna Yuan, Lin Zhang, Bohao Sun, Shaoqing Hu, Jing Zhang, Wanxin Wu and 1 more

Abstract read
In one paragraph

Article in Translational cancer research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Leiyan WeiDepartment of Pathology, Affiliated Hospital of Jiaxing University/The First Hospital of Jiaxing, Jiaxing, China.
Wu ZhuDepartment of Blood Transfusion, Affiliated Women and Children Hospital of Jiaxing University, Jiaxing, China.ORCID https://orcid.org/0000-0002-7184-8231
Zhiqin GuoDepartment of Pathology, Affiliated Hospital of Jiaxing University/The First Hospital of Jiaxing, Jiaxing, China.
Hong ZhangDepartment of Pathology, Affiliated Hospital of Jiaxing University/The First Hospital of Jiaxing, Jiaxing, China.
Linna YuanDepartment of Pathology, Affiliated Hospital of Jiaxing University/The First Hospital of Jiaxing, Jiaxing, China.
Lin ZhangDepartment of Pathology, Affiliated Hospital of Jiaxing University/The First Hospital of Jiaxing, Jiaxing, China.
Bohao SunDepartment of Pathology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Shaoqing HuDepartment of Pathology, Affiliated Hospital of Jiaxing University/The First Hospital of Jiaxing, Jiaxing, China.
Jing ZhangDepartment of Pathology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Wanxin WuDepartment of Pathology, Affiliated Hospital of Jiaxing University/The First Hospital of Jiaxing, Jiaxing, China.
Xiangyi ChenDepartment of Pathology, Affiliated Hospital of Jiaxing University/The First Hospital of Jiaxing, Jiaxing, China.ORCID https://orcid.org/0009-0000-4329-9012

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Colorectal cancer (CRC) remains a significant global health challenge, marked by high incidence and mortality rates, as well as ongoing limitations in current diagnostic and therapeutic strategies. Accurate prognostic evaluation and the customization of treatment to meet the individual requirements of patients are of paramount importance. gamma-aminobutyric acid type A receptor subunit delta ( Methods: Transcriptomic data and clinical records of CRC patients were retrieved from The Cancer Genome Atlas (TCGA). A prognostic signature based on neurotransmitter receptor-associated genes (NRGs) was developed using the least absolute shrinkage and selection operator (LASSO) Cox regression model. Functional enrichment analyses were performed. Immune cell infiltration was assessed via single-sample Gene Set Enrichment Analysis (ssGSEA). The correlation between Results: Conclusions:

Indexed as

colorectal cancer (CRC)diagnosisGABRDimmune cell infiltrationprognosis

Identifiers

PMID42180912
PMCPMC13190785

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.