Evidence map›Paper›PMID 42180983›Full record

ArticleTranslational cancer research2026

Molecular mechanism of

Huaibin Zhang, Rongxuan Liu, Xiaorong Liu, Wenqiang Liang, Wenji Wang, Yongping Wang

Abstract read
In one paragraph

Article in Translational cancer research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Huaibin Zhang *Department of Orthopedics, The First Hospital of Lanzhou University, Lanzhou, China.
Rongxuan Liu *Hainan Medical University, Haikou, China.
Xiaorong LiuDepartment of Laboratory, The Second Affiliated Hospital of Hainan Medical University, Haikou, China.
Wenqiang LiangDepartment of Orthopedics, The First Hospital of Lanzhou University, Lanzhou, China.
Wenji WangDepartment of Orthopedics, The First Hospital of Lanzhou University, Lanzhou, China.
Yongping WangDepartment of Orthopedics, The Second Affiliated Hospital of Hainan Medical University, Haikou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Osteosarcoma is a malignant bone tumor with high incidence in children and adolescents, and its prognosis is generally poor. Current comprehensive treatments are limited by tumor recurrence, lung metastasis, and chemoresistance, necessitating further elucidation of the underlying molecular mechanisms and the development of novel therapeutic targets. MicroRNAs (miRNAs) participate in the malignant biological behavior of tumors by post-transcriptionally regulating target genes. Previous studies have shown that Methods: The expression levels of miRNA and protein were detected by real-time polymerase chain reaction (RT-PCR) and Western blot. Bioinformatics methods were used to predict whether there were binding sites between Results: Conclusions: The high expression of

Indexed as

FBXW7microRNA (miRNA)miR-27a-3pOsteosarcomaWnt/β-catenin signaling pathway

Identifiers

PMID42180983
PMCPMC13190890

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.