ArticleAnnals of joint2026
Dynapenic abdominal obesity and symptomatic knee osteoarthritis: results from a large cross-sectional study of middle-aged and older adults in China.
Article in Annals of joint, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
Background: Knee osteoarthritis (KOA) is a major cause of disability among middle-aged and older adults worldwide. Emerging evidence suggests that muscle strength may be more relevant than muscle mass for functional outcomes, yet the combined impact of dynapenia and abdominal obesity remains insufficiently explored. The aim of this study was to investigate the association between dynapenic abdominal obesity (DAO) and symptomatic KOA in Chinese adults. Methods: This cross-sectional study analyzed data from 7,418 participants aged 45 years and older from the 2015 China Health and Retirement Longitudinal Study (CHARLS). Symptomatic KOA was defined based on physician-diagnosed osteoarthritis accompanied by self-reported knee pain. Participants were categorized into four phenotypes according to grip strength and waist circumference: non-dynapenic/non-abdominal obesity, dynapenic/non-abdominal obesity, non-dynapenic/abdominal obesity, and DAO. Results: The overall prevalence of symptomatic KOA was 9.75% and differed significantly across phenotypes. After adjustment for potential confounders, individuals with DAO showed the strongest association with symptomatic KOA, whereas abdominal obesity alone was not independently associated. Higher grip strength was consistently associated with a lower likelihood of symptomatic KOA. Age-stratified analyses revealed a stronger association of DAO with symptomatic KOA in individuals younger than 60 years, while no significant association was observed in older participants. Conclusions: DAO is associated with an increased likelihood of symptomatic KOA, with dynapenia playing a more prominent role than abdominal obesity alone. The age-related heterogeneity observed suggests that maintaining muscle strength may be particularly important for KOA prevention in midlife.
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