ArticleRSC advances2026
Curcumin derivatives with 1,5-diaryl-3-oxo-1,4-pentadiene: novel dual-function lead compounds showing anticancer and MDR reversal effects.
Article in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
1,5-Diaryl-3-oxo-1,4-pentadiene is an excellent pharmacophore derived from Curcumin. Synthesis of six focused 1,5-diaryl-3-oxo-1,4-pentadiene libraries (1a-1e, 2a-2e, 3a-3e, 4a-4e, 5a-5e and intermediates A-E) and cytotoxicity screening identified compounds 1d-5d with N-3-F-PhCH
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.