Evidence map›Paper›PMID 42182452›Full record

ArticlebioRxiv : the preprint server for biology2026

Glutamine codon-driven translational readthrough reveals context-dependent stop codon decoding fidelity.

Jessica M Leslie, Kaitlin Morse, Sarah Swerdlow, Gloria A Brar, Elçin Ünal

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jessica M LeslieDepartment of Molecular and Cell Biology, Barker Hall, University of California, Berkeley, CA, USA, 94720.ORCID 0000-0002-3964-8686
Kaitlin MorseDepartment of Molecular and Cell Biology, Barker Hall, University of California, Berkeley, CA, USA, 94720.ORCID 0000-0001-5738-0014
Sarah SwerdlowDepartment of Molecular and Cell Biology, Barker Hall, University of California, Berkeley, CA, USA, 94720.ORCID 0009-0006-5398-3532
Gloria A BrarDepartment of Molecular and Cell Biology, Barker Hall, University of California, Berkeley, CA, USA, 94720.ORCID 0000-0002-8560-9581
Elçin ÜnalDepartment of Molecular and Cell Biology, Barker Hall, University of California, Berkeley, CA, USA, 94720.ORCID 0000-0002-6768-609X

Funding

Illuminating the gene regulatory strategies underlying yeast meiosis and beyondR35GM134886 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI Gloria Ann Brar · 2020 to 2026
$3.1M
Developmental Regulation of Gene Expression by Long Undecoded Transcript IsoformsR01GM140005 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI UNAL, ELCIN · 2021 to 2024
$1.3M
NIGMS NIH HHS R01 GM140005NIGMS NIH HHS R35 GM134886
6 · The paper itself

Abstract

Deviations from the canonical genetic code include reassignment of UAA/UAG stop codons to glutamine in divergent eukaryotes, and tRNA

Indexed as

glutamine codonpolyQpreMATure stop codon[PSI+] prionribosome profilingtranslational readthroughtranslational terminationtRNAGln

Identifiers

PMID42182452
PMCPMC13192750

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.