ArticleJournal of thoracic disease2026
Incidence and risk factors of vaccination hesitancy among early-stage lung cancer patients: a cross-sectional study.
Article in Journal of thoracic disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Patients with lung cancer are highly prevalent and vulnerable to coronavirus disease 2019 (COVID-19), and vaccination is believed to be the most effective weapon to control this epidemic. Besides, COVID-19 vaccination is always withheld among patients with advanced lung cancer receiving therapy. Thus, this study aims to explore the prevalence of COVID-19 vaccination hesitancy and identify its associated factors in patients with early-stage lung cancer. Methods: A cross-sectional study of 728 patients with early-stage lung cancer before surgery was conducted to assess their level of knowledge, attitudes and hesitancy toward COVID-19 vaccination at Tianjin Medical University Cancer Hospital and Institute, from May to November 2023 in China. Multivariate logistic regression analysis was used to identify the factors influencing the likelihood of receiving a COVID-19 vaccination among early-stage lung cancer patients. Results: A total of 151 (20.7%) preoperative lung cancer patients with early stage reported concerns about the acceptance of COVID-19 vaccines. Multivariate logistic regression analysis revealed that admitted patients with early-stage lung cancer before surgery who thought the vaccine was not safe ( Conclusions: This study provides preliminary estimates of the rate of COVID-19 vaccination hesitancy among preoperative patients with early-stage lung cancer. The safety of COVID-19 vaccines remains a key determinant of vaccination acceptance. Research on the safety and efficacy of COVID-19 vaccines among patients with lung cancer is urgently needed to promote a global vaccination campaign.
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