Evidence map›Paper›PMID 42185035›Full record

Trial reportExperimental physiology2026

The effect of pre-exercise hyperventilation on repeated high-intensity inclined sprint performance.

Leon Fesseler, Andreas Patzak, Viktor Heinz, Ngan-Ha Stella Le, Oliver Opatz, Niklas Pilz, Tomas Lucca Bothe

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Experimental physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Leon FesselerInstitute of Physiology, Center for Space Medicine and Extreme Environments Berlin, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.ORCID https://orcid.org/0009-0001-3420-5915
Andreas PatzakInstitute of Translational Physiology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.ORCID https://orcid.org/0000-0002-1088-6875
Viktor HeinzInstitute of Physiology, Center for Space Medicine and Extreme Environments Berlin, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.ORCID https://orcid.org/0009-0002-5363-793X
Ngan-Ha Stella LeInstitute of Physiology, Center for Space Medicine and Extreme Environments Berlin, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Oliver OpatzInstitute of Physiology, Center for Space Medicine and Extreme Environments Berlin, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Niklas PilzInstitute of Physiology, Center for Space Medicine and Extreme Environments Berlin, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Tomas Lucca BotheInstitute of Sport Science, Leibnitz University Hannover, Hannover, Germany.

Funding

Bundesministerium für Wirtschaft und Klimaschutz (BMWK) 16SV9251Charité - Universitätsmedizin BerlinDLR 33150WB2330
6 · The paper itself

Abstract

High-intensity exercise induces systemic acidosis, which contributes to muscular performance decline. Controlled pre-exercise hyperventilation has been proposed as a non-invasive intervention to induce respiratory alkalosis and counteract acidosis-related acute fatigue. In this study, we hypothesized that a real-world-applicable pre-exercise hyperventilation protocol can improve incline sprint performance. This randomized, single-centre, controlled crossover study included 36 recreational athletes aged 18-40 years. Each participant completed a series of three inclined treadmill interval sprints on two separate days: one with pre-exercise hyperventilation and one without. Respiratory parameters were measured via spirometry, and post-sprint capillary blood gas analysis was performed. Pre-exercise hyperventilation resulted in higher mean CO

Indexed as

Athletic PerformanceExerciseHyperventilationRunningAcidosisAdolescentAdultAlkalosis, RespiratoryBlood Gas AnalysisCarbon DioxideCross-Over StudiesExercise TestFemaleHumansMaleYoung AdultCarbon Dioxidehyperventilationrespiratory alkalosissprint interval training

Identifiers

PMID42185035
PMCPMC13327302

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.